Professeur, Aix-Marseille Université
Page personelle / Personal webpage
Publications
2020
Patrick Bertrand (ed).
Electron Paramagnetic Resonance Spectroscopy: Applications.
Electron Paramagnetic Resonance Spectroscopy: Applications, 2020.
DOI: 10.1007/978-3-030-39668-8
2014
Julien G.J. Jacques, Vincent Fourmond, Pascal Arnoux, Monique Sabaty, Emilien Etienne, Sandrine Grosse, Frédéric Biaso, Patrick Bertrand, David Pignol, Christophe Léger, Bruno Guigliarelli, Bénédicte Burlat.
Reductive activation in periplasmic nitrate reductase involves chemical modifications of the Mo-cofactor beyond the first coordination sphere of the metal ion.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2014, 1837 (2), 277 - 286.
DOI: 10.1016/j.bbabio.2013.10.013
HAL: hal-01481487v1
Claudio Greco, Vincent Fourmond, Carole Baffert, Po-hung Wang, Sébastien Dementin, Patrick Bertrand, Maurizio Bruschi, Jochen Blumberger, Luca de Gioia, Christophe Léger.
Combining experimental and theoretical methods to learn about the reactivity of gas-processing metalloenzymes.
Energy Environ. Sci., 2014, 108 (11), 2066 - 3573.
DOI: 10.1039/C4EE01848F
HAL: hal-01211585v1
2013
Patrick Bertrand.
Theoretical and Computational Chemistry Series.
2013, 379 - 407.
DOI: 10.1039/9781849737753-00379
2012
Abbas Abou Hamdan, Sébastien Dementin, Pierre-Pol Liebgott, Oscar Gutierrez-Sanz, Pierre Richaud, Antonio L. De Lacey, Marc Rousset, Patrick Bertrand, Laurent Cournac, Christophe Léger.
Understanding and Tuning the Catalytic Bias of Hydrogenase.
J. Am. Chem. Soc., 2012, 134 (20), 8368 - 8371.
DOI: 10.1021/ja301802r
HAL: hal-00748324v1
2011
Sébastien Dementin, Bénédicte Burlat, Vincent Fourmond, Fanny Leroux, Pierre-Pol Liebgott, Abbas Abou Hamdan, Christophe Léger, Marc Rousset, Bruno Guigliarelli, Patrick Bertrand.
Rates of Intra- and Intermolecular Electron Transfers in Hydrogenase Deduced from Steady-State Activity Measurements.
J. Am. Chem. Soc., 2011, 133 (26), 10211 - 10221.
DOI: 10.1021/ja202615a
HAL: hal-00677402v1
Carole Baffert, Luca Bertini, Thomas Lautier, Claudio Greco, Kateryna Sybirna, Pierre Ezanno, Emilien Etienne, Philippe Soucaille, Patrick Bertrand, Hervé Bottin, Isabelle Meynial-Salles, Luca De Gioia, Christophe Léger.
CO Disrupts the Reduced H-Cluster of FeFe Hydrogenase. A Combined DFT and Protein Film Voltammetry Study.
J. Am. Chem. Soc., 2011, 133 (7), 2096 - 2099.
DOI: 10.1021/ja110627b
HAL: hal-02652182v1
Thomas Lautier, Pierre Ezanno, Carole Baffert, Vincent Fourmond, Laurent Cournac, Juan C. Fontecilla-Camps, Philippe Soucaille, Patrick Bertrand, Isabelle Meynial-Salles, Christophe Léger.
The quest for a functional substrate access tunnel in FeFe hydrogenase.
Faraday Discuss., 2011, 304, 55 - 407.
DOI: 10.1039/c004099c
HAL: hal-02646834
2010
Patrick Bertrand.
Electron Paramagnetic Resonance Spectroscopy: Fundamentals.
Electron Paramagnetic Resonance Spectroscopy: Fundamentals, 2010.
DOI: 10.1007/978-3-030-39663-3
Fanny Leroux, Pierre-Pol Liebgott, Laurent Cournac, Pierre Richaud, Arlette Kpebe, Bénedicte Burlat, Bruno Guigliarelli, Patrick Bertrand, Christophe Léger, Marc Rousset.
Is engineering O2-tolerant hydrogenases just a matter of reproducing the active sites of the naturally occurring O2-resistant enzymes?.
International Journal of Hydrogen Energy, 2010, 35 (19), 10770 - 10777.
DOI: 10.1016/j.ijhydene.2010.02.071
HAL: hal-01977635v1
Maria-Eirini Pandelia, Vincent Fourmond, Pascale Tron-Infossi, Elisabeth Lojou, Patrick Bertrand, Christophe Léger, Marie-Thérèse Giudici-Orticoni, Wolfgang Lubitz.
Membrane-Bound Hydrogenase I from the Hyperthermophilic Bacterium Aquifex aeolicus: Enzyme Activation, Redox Intermediates and Oxygen Tolerance.
J. Am. Chem. Soc., 2010, 132 (20), 6991 - 7004.
DOI: 10.1021/ja910838d
HAL: hal-00686880v1
Vincent Fourmond, Pascale Infossi, Marie-Thérèse Giudici-Orticoni, Patrick Bertrand, Christophe Léger.
“Two-Step” Chronoamperometric Method for Studying the Anaerobic Inactivation of an Oxygen Tolerant NiFe Hydrogenase.
J. Am. Chem. Soc., 2010, 132 (13), 4848 - 4857.
DOI: 10.1021/ja910685j
HAL: hal-00677470
Vincent Fourmond, Bénédicte Burlat, Sébastien Dementin, Monique Sabaty, Pascal Arnoux, Émilien Étienne, Bruno Guigliarelli, Patrick Bertrand, David Pignol, Christophe Léger.
Dependence of Catalytic Activity on Driving Force in Solution Assays and Protein Film Voltammetry: Insights from the Comparison of Nitrate Reductase Mutants.
Biochemistry, 2010, 49 (11), 2424 - 2432.
DOI: 10.1021/bi902140e
HAL: hal-00677461
Vincent Fourmond, Monique Sabaty, Pascal Arnoux, Patrick Bertrand, David Pignol, Christophe Léger.
Reassessing the Strategies for Trapping Catalytic Intermediates during Nitrate Reductase Turnover.
J. Phys. Chem. B, 2010, 114 (9), 3341 - 3347.
DOI: 10.1021/jp911443y
HAL: hal-00677469
Pierre-Pol Liebgott, Fanny Leroux, Bénédicte Burlat, Sébastien Dementin, Carole Baffert, Thomas Lautier, Vincent Fourmond, Pierre Ceccaldi, Christine Cavazza, Isabelle Meynial-Salles, Philippe Soucaille, Juan Carlos Fontecilla-Camps, Bruno Guigliarelli, P.
Relating diffusion along the substrate tunnel and oxygen sensitivity in hydrogenase.
Nat Chem Biol, 2010, 6, 63 - 70.
DOI: 10.1038/nchembio.276
HAL: hal-01977629
2009
Vincent Fourmond, Kevin Hoke, Hendrik A. Heering, Carole Baffert, Fanny Leroux, Patrick Bertrand, Christophe Léger.
SOAS: A free program to analyze electrochemical data and other one-dimensional signals.
Bioelectrochemistry, 2009, 76 (1-2), 141 - 147.
DOI: 10.1016/j.bioelechem.2009.02.010
HAL: hal-00402940v1
Vincent Fourmond, Thomas Lautier, Carole Baffert, Fanny Leroux, Pierre-Pol Liebgott, Sébastien Dementin, Marc Rousset, Pascal Arnoux, David Pignol, Isabelle Meynial-Salles, Phillippe Soucaille, Patrick Bertrand, Christophe Léger.
Correcting for Electrocatalyst Desorption and Inactivation in Chronoamperometry Experiments.
Anal. Chem., 2009, 81 (8), 2962 - 2968.
DOI: 10.1021/ac8025702
HAL: hal-01825488v1
2008
Vincent Fourmond, Bénédicte Burlat, Sébastien Dementin, Pascal Arnoux, Monique Sabaty, Séverine Boiry, Bruno Guigliarelli, Patrick Bertrand, David Pignol, Christophe Léger.
Major Mo(V) EPR Signature of Rhodobacter sphaeroides Periplasmic Nitrate Reductase Arising from a Dead-End Species That Activates upon Reduction. Relation to Other Molybdoenzymes from the DMSO Reductase Family.
J. Phys. Chem. B, 2008, 112 (48), 15478 - 15486.
DOI: 10.1021/jp807092y
HAL: hal-00336002
F. Leroux, S. Dementin, B. Burlat, L. Cournac, A. Volbeda, S. Champ, L. Martin, B. Guigliarelli, P. Bertrand, J. Fontecilla-Camps, M. Rousset, C. Leger.
Experimental approaches to kinetics of gas diffusion in hydrogenase.
Proceedings of the National Academy of Sciences, 2008, 105 (32), 11188 - 11193.
DOI: 10.1073/pnas.0803689105
HAL: hal-00336010v1
Christophe Léger, Patrick Bertrand.
Direct Electrochemistry of Redox Enzymes as a Tool for Mechanistic Studies.
Chem. Rev., 2008, 108 (7), 2379 - 2438.
DOI: 10.1021/cr0680742
HAL: hal-01211439v1
Carole Baffert, Marie Demuez, Laurent Cournac, Bénédicte Burlat, Bruno Guigliarelli, Patrick Bertrand, Laurence Girbal, Christophe Léger.
Hydrogen-Activating Enzymes: Activity Does Not Correlate with Oxygen Sensitivity.
Angew. Chem. Int. Ed., 2008, 47 (11), 2052 - 2054.
DOI: 10.1002/anie.200704313
HAL: hal-00336018
2007
Pascal Lanciano, Adrien Savoyant, Stéphane Grimaldi, Axel Magalon, Bruno Guigliarelli, Patrick Bertrand.
New Method for the Spin Quantitation of [4Fe−4S]+ Clusters with S = 3 / 2. Application to the FS0 Center of the NarGHI Nitrate Reductase from Escherichia coli.
J. Phys. Chem. B, 2007, 111 (48), 13632 - 13637.
DOI: 10.1021/jp075243t
HAL: hal-00336023v1
Patrick Bertrand, Bettina Frangioni, Sébastien Dementin, Monique Sabaty, Pascal Arnoux, Bruno Guigliarelli, David Pignol, Christophe Léger.
Effects of Slow Substrate Binding and Release in Redox Enzymes: Theory and Application to Periplasmic Nitrate Reductase.
J. Phys. Chem. B, 2007, 111 (34), 10300 - 10311.
DOI: 10.1021/jp074340j
HAL: hal-00336030
Pascal Lanciano, Axel Magalon, Patrick Bertrand, Bruno Guigliarelli, Stéphane Grimaldi.
High-Stability Semiquinone Intermediate in Nitrate Reductase A (NarGHI) from Escherichia coli Is Located in a Quinol Oxidation Site Close to Heme bD.
Biochemistry, 2007, 46 (18), 5323 - 5329.
DOI: 10.1021/bi700074y
HAL: hal-00336035v1
2006
M. Gabriela Almeida, Célia M. Silveira, Bruno Guigliarelli, Patrick Bertrand, José J.G. Moura, Isabel Moura, Christophe Léger.
A needle in a haystack: The active site of the membrane-bound complex cytochrome c nitrite reductase.
2006, 581 (2), 284 - 288.
DOI: 10.1016/j.febslet.2006.12.023
HAL: hal-00336044
Sébastien Dementin, Valérie Belle, Patrick Bertrand, Bruno Guigliarelli, Géraldine Adryanczyk-Perrier, Antonio L. De Lacey, Victor M. Fernandez, Marc Rousset, Christophe Léger.
Changing the Ligation of the Distal [4Fe4S] Cluster in NiFe Hydrogenase Impairs Inter- and Intramolecular Electron Transfers.
J. Am. Chem. Soc., 2006, 128 (15), 5209 - 5218.
DOI: 10.1021/ja060233b
HAL: hal-00335157v1
Christophe Léger, Florence Lederer, Bruno Guigliarelli, Patrick Bertrand.
Electron Flow in Multicenter Enzymes: Theory, Applications, and Consequences on the Natural Design of Redox Chains.
J. Am. Chem. Soc., 2006, 128 (1), 180 - 187.
DOI: 10.1021/ja055275z
HAL: hal-00336055v1
2005
Claude More, Marcel Asso, Guy Roger, Bruno Guigliarelli, Jorge Caldeira, José Moura, Patrick Bertrand.
Study of the Spin−Spin Interactions between the Metal Centers of Desulfovibrio gigas Aldehyde Oxidoreductase: Identification of the Reducible Sites of the [2Fe-2S] 1+,2+ Clusters.
Biochemistry, 2005, 44 (34), 11628 - 11635.
DOI: 10.1021/bi0510025
HAL: hal-00336065v1
Stéphane Grimaldi, Pascal Lanciano, Patrick Bertrand, Francis Blasco, Bruno Guigliarelli.
Evidence for an EPR-Detectable Semiquinone Intermediate Stabilized in the Membrane-Bound Subunit NarI of Nitrate Reductase A (NarGHI) from Escherichia coli.
Biochemistry, 2005, 44 (4), 1300 - 1308.
DOI: 10.1021/bi048009r
HAL: hal-03549620v1
2004
Christophe Léger, Sébastien Dementin, Patrick Bertrand, Marc Rousset, Bruno Guigliarelli.
Inhibition and Aerobic Inactivation Kinetics of Desulfovibrio fructosovorans NiFe Hydrogenase Studied by Protein Film Voltammetry.
J. Am. Chem. Soc., 2004, 126 (38), 12162 - 12172.
DOI: 10.1021/ja046548d
HAL: hal-00336069
Bettina Frangioni, Pascal Arnoux, Monique Sabaty, David Pignol, Patrick Bertrand, Bruno Guigliarelli, Christophe Léger.
In Rhodobacter sphaeroides Respiratory Nitrate Reductase, the Kinetics of Substrate Binding Favors Intramolecular Electron Transfer.
J. Am. Chem. Soc., 2004, 126 (5), 1328 - 1329.
DOI: 10.1021/ja0384072
HAL: hal-00338609v1