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Maître de Conférence, Aix-Marseille Université

+33 4 91 16 45 41

Equipe / Group: BIP 05



Aurore Jacq-Bailly, Martino Benvenuti, Natalie Payne, Arlette Kpebe, Christina Felbek, Vincent Fourmond, Christophe Léger, Myriam Brugna, Carole Baffert.
Electrochemical Characterization of a Complex FeFe Hydrogenase, the Electron-Bifurcating Hnd From Desulfovibrio fructosovorans.
Front. Chem., 2021, 8. DOI: 10.3389/fchem.2020.573305 HAL: hal-03103487v1


Robert Van Lis, Sabine Brugière, Carole Baffert, Yohann Couté, Wolfgang Nitschke, Ariane Atteia.
Hybrid cluster proteins in a photosynthetic microalga.
FEBS J, 2019, 33 (1), 1870 -. DOI: 10.1111/febs.15025 HAL: hal-02284985v1

Carole Baffert, Arlette Kpebe, Luisana Avilan, Myriam Brugna.
Hydrogenases and H2 metabolism in sulfate-reducing bacteria of the Desulfovibrio genus..
Advances in Microbial Physiology., 2019, 74, 143 - 189. DOI: 10.1016/bs.ampbs.2019.03.001

Melisa del Barrio, Chloé Guendon, Arlette Kpebe, Carole Baffert, Vincent Fourmond, Myriam Brugna, Christophe Léger.
Valine-to-Cysteine Mutation Further Increases the Oxygen Tolerance of Escherichia coli NiFe Hydrogenase Hyd-1.
ACS Catal., 2019, 9 (5), 4084 - 4088. DOI: 10.1021/acscatal.9b00543 HAL: hal-02104593v1


Arlette Kpebe, Martino Benvenuti, Chloé Guendon, Amani Rebai, Victoria Fernandez, Sébastien Le Laz, Emilien Etienne, Bruno Guigliarelli, Gabriel García-Molina, Antonio L. de Lacey, Carole Baffert, Myriam Brugna.
A new mechanistic model for an O2-protected electron-bifurcating hydrogenase, Hnd from Desulfovibrio fructosovorans.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2018, 1859 (12), 1302 - 1312. DOI: 10.1016/j.bbabio.2018.09.364 HAL: hal-01928576v1

Melisa del Barrio, Matteo Sensi, Christophe Orain, Carole Baffert, Sébastien Dementin, Vincent Fourmond, Christophe Léger.
Electrochemical Investigations of Hydrogenases and Other Enzymes That Produce and Use Solar Fuels.
Acc. Chem. Res., 2018, 51 (3), 769 - 777. DOI: 10.1021/acs.accounts.7b00622 HAL: hal-01745738v1

Frauke Baymann, Barbara Schoepp-Cothenet, Simon Duval, Marianne Guiral, Myriam Brugna, Carole Baffert, Michael J. Russell, Wolfgang Nitschke.
On the Natural History of Flavin-Based Electron Bifurcation.
Front. Microbiol., 2018, 8, 357 -. DOI: 10.3389/fmicb.2018.01357 HAL: hal-01828959v1

Charles Gauquelin, Carole Baffert, Pierre Richaud, Emma Kamionka, Emilien Etienne, David Guieysse, Laurence Girbal, Vincent Fourmond, Isabelle André, Bruno Guigliarelli, Christophe Léger, Philippe Soucaille, Isabelle Meynial-Salles.
Roles of the F-domain in [FeFe] hydrogenase.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2018, 1859 (2), 69 - 77. DOI: 10.1016/j.bbabio.2017.08.010 HAL: cea-01950818


Adam Kubas, Christophe Orain, David De Sancho, Laure Saujet, Matteo Sensi, Charles Gauquelin, Isabelle Meynial-Salles, Philippe Soucaille, Hervé Bottin, Carole Baffert, Vincent Fourmond, Robert B. Best, Jochen Blumberger, Christophe Léger.
Mechanism of O2 diffusion and reduction in FeFe hydrogenases.
Nature Chem, 2017, 11 (1), 205 - 95. DOI: 10.1038/nchem.2592 HAL: hal-01406025v1

Matteo Sensi, Melisa del Barrio, Carole Baffert, Vincent Fourmond, Christophe Léger.
New perspectives in hydrogenase direct electrochemistry.
Current Opinion in Electrochemistry, 2017, 5 (1), 135 - 145. DOI: 10.1016/j.coelec.2017.08.005 HAL: hal-01614142v1

Matteo Sensi, Carole Baffert, Laura Fradale, Charles Gauquelin, Philippe Soucaille, Isabelle Meynial-Salles, Hervé Bottin, Luca de Gioia, Maurizio Bruschi, Vincent Fourmond, Christophe Léger, Luca Bertini.
Photoinhibition of FeFe Hydrogenase.
ACS Catal., 2017, 7 (10), 7378 - 7387. DOI: 10.1021/acscatal.7b02252 HAL: hal-01613876v1


Eunsun Kim, Abdellah Felouat, Elena Zaborova, Jean-Charles Ribierre, Jeong Weon Wu, Sébastien Senatore, Cédric Matthews, Pierre-François Lenne, Carole Baffert, Artak Karapetyan, Michel Giorgi, Denis Jacquemin, Miguel Ponce-Vargas, Boris Le Guennic, Frédér.
Borondifluoride complexes of hemicurcuminoids as bio-inspired push–pull dyes for bioimaging.
Org. Biomol. Chem., 2016, 125 (4), 054103 - 1324. DOI: 10.1039/C5OB02295A HAL: hal-01413409v1

Matteo Sensi, Carole Baffert, Claudio Greco, Giorgio Caserta, Charles Gauquelin, Laure Saujet, Marc Fontecave, Souvik Roy, Vincent Artero, Philippe Soucaille, Isabelle Meynial-Salles, Hervé Bottin, Luca de Gioia, Vincent Fourmond, Christophe Léger, Luca B.
Reactivity of the Excited States of the H-Cluster of FeFe Hydrogenases.
J. Am. Chem. Soc., 2016, 138 (41), 13612 - 13618. DOI: 10.1021/jacs.6b06603 HAL: hal-01889471v1


Christophe Orain, Laure Saujet, Charles Gauquelin, Philippe Soucaille, Isabelle Meynial-Salles, Carole Baffert, Vincent Fourmond, Hervé Bottin, Christophe Léger.
Electrochemical Measurements of the Kinetics of Inhibition of Two FeFe Hydrogenases by O2 2 Demonstrate That the Reaction Is Partly Reversible.
J. Am. Chem. Soc., 2015, 137 (39), 12580 - 12587. DOI: 10.1021/jacs.5b06934 HAL: hal-01211469v1


Claudio Greco, Vincent Fourmond, Carole Baffert, Po-hung Wang, Sébastien Dementin, Patrick Bertrand, Maurizio Bruschi, Jochen Blumberger, Luca de Gioia, Christophe Léger.
Combining experimental and theoretical methods to learn about the reactivity of gas-processing metalloenzymes.
Energy Environ. Sci., 2014, 108 (11), 2066 - 3573. DOI: 10.1039/C4EE01848F HAL: hal-01211585v1

Viviane Hajj, Carole Baffert, Kateryna Sybirna, Isabelle Meynial-Salles, Philippe Soucaille, Hervé Bottin, Vincent Fourmond, Christophe Léger.
FeFe hydrogenase reductive inactivation and implication for catalysis.
Energy Environ. Sci., 2014, 6 (2), 2460 - 719. DOI: 10.1039/C3EE42075B HAL: hal-01481475v1

Vincent Fourmond, Claudio Greco, Kateryna Sybirna, Carole Baffert, Po-Hung Wang, Pierre Ezanno, Marco Montefiori, Maurizio Bruschi, Isabelle Meynial-Salles, Philippe Soucaille, Jochen Blumberger, Hervé Bottin, Luca De Gioia, Christophe Léger.
The oxidative inactivation of FeFe hydrogenase reveals the flexibility of the H-cluster.
Nature Chem, 2014, 130 (4), 4533 - 342. DOI: 10.1038/nchem.1892 HAL: hal-01481520v1


Kateryna Sybirna, Pierre Ezanno, Carole Baffert, Christophe Léger, Hervé Bottin.
Arginine171 of Chlamydomonas reinhardtii [Fe–Fe] hydrogenase HydA1 plays a crucial role in electron transfer to its catalytic center.
International Journal of Hydrogen Energy, 2013, 38 (7), 2998 - 3002. DOI: 10.1016/j.ijhydene.2012.12.078

Toshiko Miyake, Maurizio Bruschi, Ugo Cosentino, Carole Baffert, Vincent Fourmond, Christophe Léger, Giorgio Moro, Luca De Gioia, Claudio Greco.
Does the environment around the H-cluster allow coordination of the pendant amine to the catalytic iron center in [FeFe] hydrogenases? Answers from theory.
J Biol Inorg Chem, 2013, 13 (6), 3580 - 700. DOI: 10.1007/s00775-013-1014-4 HAL: hal-03023214

Abbas Abou Hamdan, Bénédicte Burlat, Oscar Gutiérrez-Sanz, Pierre-Pol Liebgott, Carole Baffert, Antonio L De Lacey, Marc Rousset, Bruno Guigliarelli, Christophe Léger, Sébastien Dementin.
O2-independent formation of the inactive states of NiFe hydrogenase.
Nat Chem Biol, 2013, 118 (1), 12989 - 17. DOI: 10.1038/NCHEMBIO.1110 HAL: hal-01556905v1

Sylvain Chambon, Anthony D'Aléo, Carole Baffert, Guillaume Wantz, Frédéric Fages.
Solution-processed bulk heterojunction solar cells based on BF2–hydroxychalcone complexes.
Chem. Commun., 2013, 94 (34), 6849 -. DOI: 10.1039/C3CC41351A HAL: hal-00869954v1

Vincent Fourmond, Carole Baffert, Kateryna Sybirna, Thomas Lautier, Abbas Abou Hamdan, Sébastien Dementin, Philippe Soucaille, Isabelle Meynial-Salles, Hervé Bottin, Christophe Léger.
Steady-State Catalytic Wave-Shapes for 2-Electron Reversible Electrocatalysts and Enzymes.
J. Am. Chem. Soc., 2013, 135 (10), 3926 - 3938. DOI: 10.1021/ja311607s HAL: hal-01268145v1

Vincent Fourmond, Carole Baffert, Kateryna Sybirna, Sébastien Dementin, Abbas Abou-Hamdan, Isabelle Meynial-Salles, Philippe Soucaille, Hervé Bottin, Christophe Léger.
The mechanism of inhibition by H2 of H2-evolution by hydrogenases.
Chem. Commun., 2013, 109 (61), 19916 -. DOI: 10.1039/C3CC43297A HAL: hal-01268212v1


Robert van Lis, Carole Baffert, Yohann Couté, Wolfgang Nitschke, Ariane Atteia.
Chlamydomonas reinhardtii Chloroplasts Contain a Homodimeric Pyruvate:Ferredoxin Oxidoreductase That Functions with FDX1.
Plant Physiol., 2012, 161 (1), 57 - 71. DOI: 10.1104/pp.112.208181 HAL: hal-01601845v1

Carole Baffert, Kateryna Sybirna, Pierre Ezanno, Thomas Lautier, Viviane Hajj, Isabelle Meynial-Salles, Philippe Soucaille, Hervé Bottin, Christophe Léger.
Covalent Attachment of FeFe Hydrogenases to Carbon Electrodes for Direct Electron Transfer.
Anal. Chem., 2012, 84 (18), 7999 - 8005. DOI: 10.1021/ac301812s HAL: hal-01268277v1


Carole Baffert, Luca Bertini, Thomas Lautier, Claudio Greco, Kateryna Sybirna, Pierre Ezanno, Emilien Etienne, Philippe Soucaille, Patrick Bertrand, Hervé Bottin, Isabelle Meynial-Salles, Luca De Gioia, Christophe Léger.
CO Disrupts the Reduced H-Cluster of FeFe Hydrogenase. A Combined DFT and Protein Film Voltammetry Study.
J. Am. Chem. Soc., 2011, 133 (7), 2096 - 2099. DOI: 10.1021/ja110627b

Thomas Lautier, Pierre Ezanno, Carole Baffert, Vincent Fourmond, Laurent Cournac, Juan C. Fontecilla-Camps, Philippe Soucaille, Patrick Bertrand, Isabelle Meynial-Salles, Christophe Léger.
The quest for a functional substrate access tunnel in FeFe hydrogenase.
Faraday Discuss., 2011, 304, 55 - 407. DOI: 10.1039/c004099c


Cristina Valls, José F. Colom, Carole Baffert, Isabelle Gimbert, M. Blanca Roncero, Jean-Claude Sigoillot.
Comparing the efficiency of the laccase–NHA and laccase–HBT systems in eucalyptus pulp bleaching.
Biochemical Engineering Journal, 2010, 49 (3), 401 - 407. DOI: 10.1016/j.bej.2010.02.002

Pierre-Pol Liebgott, Fanny Leroux, Bénédicte Burlat, Sébastien Dementin, Carole Baffert, Thomas Lautier, Vincent Fourmond, Pierre Ceccaldi, Christine Cavazza, Isabelle Meynial-Salles, Philippe Soucaille, Juan Carlos Fontecilla-Camps, Bruno Guigliarelli, P.
Relating diffusion along the substrate tunnel and oxygen sensitivity in hydrogenase.
Nat Chem Biol, 2010, 275 (1), 113 - 70. DOI: 10.1038/nchembio.276 HAL: hal-01977629


Vincent Fourmond, Thomas Lautier, Carole Baffert, Fanny Leroux, Pierre-Pol Liebgott, Sébastien Dementin, Marc Rousset, Pascal Arnoux, David Pignol, Isabelle Meynial-Salles, Phillippe Soucaille, Patrick Bertrand, Christophe Léger.
Correcting for Electrocatalyst Desorption and Inactivation in Chronoamperometry Experiments.
Anal. Chem., 2009, 81 (8), 2962 - 2968. DOI: 10.1021/ac8025702 HAL: hal-01825488v1

Sophie Romain, Carole Baffert, Carole Duboc, Jean-Claude Leprêtre, Alain Deronzier, Marie-Noëlle Collomb.
Mononuclear Mn III and Mn IV Bis-terpyridine Complexes: Electrochemical Formation and Spectroscopic Characterizations.
Inorg. Chem., 2009, 48 (7), 3125 - 3131. DOI: 10.1021/ic8024342 HAL: hal-01659002v1

Vincent Fourmond, Kevin Hoke, Hendrik A. Heering, Carole Baffert, Fanny Leroux, Patrick Bertrand, Christophe Léger.
SOAS: A free program to analyze electrochemical data and other one-dimensional signals.
Bioelectrochemistry, 2009, 76 (1-2), 141 - 147. DOI: 10.1016/j.bioelechem.2009.02.010 HAL: hal-00402940v1


Carole Baffert, Marie Demuez, Laurent Cournac, Bénédicte Burlat, Bruno Guigliarelli, Patrick Bertrand, Laurence Girbal, Christophe Léger.
Hydrogen-Activating Enzymes: Activity Does Not Correlate with Oxygen Sensitivity.
Angew. Chem. Int. Ed., 2008, 71 (11), 2777 - 2054. DOI: 10.1002/anie.200704313 HAL: hal-00336018