Ingénieur de Recherche, Aix-Marseille Université
+33 4 91 16 45 41
Equipe / Group: BIP 07
Responsable technique sur la plateforme de RPE (Résonance Paramagnétique Électronique), mes priorités sont le bon état de marche des spectromètres et le soutien aux utilisateurs, internes ou externes au BIP. Hormis ces priorités, je développe, notamment, des outils numériques pour le traitement de données RPE ou les simulations RPE avec EasySpin. Je suis également membre élu du conseil d’administration de l’ARPE depuis 2016 et co-fondateur du technic’ARPE.
Publications
ORCID id: 0000-0002-5999-7904
2024
Maxime Bizet, Deborah Byrne, Frédéric Biaso, Guillaume Gerbaud, Emilien Etienne, Giuseppina Briola, Bruno Guigliarelli, Philippe Urban, Pierre Dorlet, Tamas Kalai, Gilles Truan, Marlene Martinho.
Structural insights into the semiquinone form of human Cytochrome P450 reductase by DEER distance measurements between a native flavin and a spin labelled non‐canonical amino acid.
Chemistry Eur J, 2024.
DOI: 10.1002/chem.202304307
HAL: hal-04426634
Marlène Martinho, Diane Allegro, Emilien Etienne, Cynthia Lohberger, Alessio Bonucci, Valérie Belle, Pascale Barbier.
Structural Flexibility of Tau in Its Interaction with Microtubules as Viewed by Site-Directed Spin Labeling EPR Spectroscopy.
Methods in Molecular Biology, 2024, 2754, 55 - 75.
DOI: 10.1007/978-1-0716-3629-9_3
HAL: hal-04532622v1
2023
Annalisa Pierro, Ketty Concetta Tamburrini, Hugo Leguenno, Guillaume Gerbaud, Emilien Etienne, Bruno Guigliarelli, Valérie Belle, Barbara Zambelli, Elisabetta Mileo.
In-cell investigation of the conformational landscape of the GTPase UreG by SDSL-EPR.
iScience, 2023, 26 (10), 107855.
DOI: 10.1016/j.isci.2023.107855
HAL: hal-04233485v1
Guillaume Gerbaud, Brice Barbat, Mathilde Tribout, Emilien Etienne, Valérie Belle, Badreddine Douzi, Romé Voulhoux, Alessio Bonucci.
Refining the Dynamic Network of T2SS Endopilus Tip Heterocomplex Combining cw‐EPR and Nitroxide–Gd III Distance Measurements.
ChemBioChem, 2023, 24 (15), e2023000.
DOI: 10.1002/cbic.202300099
HAL: hal-04210232v1
Pierre Nabokoff, Guillaume Brulay, Cyrielle Dol, Guillaume Gerbaud, Bruno Guigliarelli, Emilien Etienne, Emily Bloch, Fabio Ziarelli, Eric Besson, Stéphane Gastaldi.
Synthesis and Characterization of Face-to-Face Arylsulfanyl and Phenoxyl Radicals Embedded in Mesoporous Silicas.
J. Phys. Chem. C, 2023, 127 (20), 9699 - 9706.
DOI: 10.1021/acs.jpcc.3c01550
HAL: hal-04114864v1
Emilien Etienne, Annalisa Pierro, Ketty C. Tamburrini, Alessio Bonucci, Elisabetta Mileo, Marlène Martinho, Valérie Belle.
Guidelines for the Simulations of Nitroxide X-Band cw EPR Spectra from Site-Directed Spin Labeling Experiments Using SimLabel.
Molecules, 2023, 28 (3), 1348.
DOI: 10.3390/molecules28031348
HAL: hal-03971418v1
2022
Annalisa Pierro, Alessio Bonucci, Davide Normanno, Mireille Ansaldi, Eric Pilet, Olivier Ouari, Bruno Guigliarelli, Emilien Etienne, Guillaume Gerbaud, Axel Magalon, Valérie Belle, Elisabetta Mileo.
Probing Structural Dynamics of a Bacterial Chaperone in Its Native Environment by Nitroxide‐Based EPR Spectroscopy.
Chemistry A European J, 2022.
DOI: 10.1002/chem.202202249
HAL: hal-03836431
Batoul Srour, Sylvain Gervason, Maren Hellen Hoock, Beata Monfort, Kristian Want, Djabir Larkem, Nadine Trabelsi, Gautier Landrot, Andrea Zitolo, Emiliano Fonda, Emilien Etienne, Guillaume Gerbaud, Christina Sophia Müller, Jonathan Oltmanns, Jesse B. Gordon, Vishal Yadav, Malgorzata Kleczewska, Marcin Jelen, Michel B. Toledano, Rafal Dutkiewicz, David P. Goldberg, Volker Schünemann, Bruno Guigliarelli, Bénédicte Burlat, Christina Sizun, Benoit D’Autréaux.
Iron Insertion at the Assembly Site of the ISCU Scaffold Protein Is a Conserved Process Initiating Fe–S Cluster Biosynthesis.
J. Am. Chem. Soc., 2022.
DOI: 10.1021/jacs.2c06338
HAL: hal-03837292v1
Julia Rendon, Margot Di Cesare, Alexia Godet, Guillaume Gerbaud, Emilien Etienne, Vincent Chaptal, Pierre Falson, Jean-Michel Jault, Cédric Orelle, Marlène Martinho, Pierre Dorlet.
Conformational dynamics of the ABC-transporter BmrA reveals by SDSL-EPR spectroscopy.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2022, 1863.
DOI: 10.1016/j.bbabio.2022.148732
Pierre Dorlet, Guillaume Gerbaud, Emilien Etienne, Stéphane Grimaldi, Bruno Guigliarelli, Valérie Belle.
EPR-MRS site: EPR spectroscopy for the study of biomolecules.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2022, 1863, Supplement, 29.
DOI: 10.1016/j.bbabio.2022.148685
HAL: hal-03805551v1
Pierre Dorlet, Guillaume Gerbaud, Emilien Etienne, Stéphane Grimaldi, Bruno Guigliarelli, Valérie Belle.
MOSBRI- A New European Research Infrastructure for Molecular Biophysics.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2022, 1863, Supplement, 28.
DOI: 10.1016/j.bbabio.2022.148684
HAL: hal-03805560v1
2020
Annalisa Pierro, Emilien Etienne, Guillaume Gerbaud, Bruno Guigliarelli, Stefano Ciurli, Valérie Belle, Barbara Zambelli, Elisabetta Mileo.
Nickel and GTP Modulate Helicobacter pylori UreG Structural Flexibility.
Biomolecules, 2020, 10 (7), 1062.
DOI: 10.3390/biom10071062
HAL: hal-02902916v1
2019
Sybille Tachon, Eugénie Fournier, Christophe Decroos, Pascal Mansuelle, Emilien Etienne, Marc Maresca, Marlène Martinho, Valérie Belle, Thierry Tron, Ariane Jalila Simaan.
Chemical Modification of 1-Aminocyclopropane Carboxylic Acid (ACC) Oxidase: Cysteine Mutational Analysis, Characterization, and Bioconjugation with a Nitroxide Spin Label.
Mol Biotechnol, 2019, 61, 650 - 662.
DOI: 10.1007/s12033-019-00191-5
HAL: hal-02157289v1
Eugénie Fournier, Elisabetta Mileo, Emilien Etienne, Guillaume Gerbaud, Valérie Belle, Marlène Martinho.
Spin labels: spies in the heart of proteins.
Actualité Chimique, 2019, 443.
(voir / see)
2018
Arlette Kpebe, Martino Benvenuti, Chloé Guendon, Amani Rebai, Victoria Fernandez, Sébastien Le Laz, Emilien Etienne, Bruno Guigliarelli, Gabriel García-Molina, Antonio L. de Lacey, Carole Baffert, Myriam Brugna.
A new mechanistic model for an O2-protected electron-bifurcating hydrogenase, Hnd from Desulfovibrio fructosovorans.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2018, 1859 (12), 1302 - 1312.
DOI: 10.1016/j.bbabio.2018.09.364
HAL: hal-01928576v1
Marlène Martinho, Diane Allegro, Isabelle Huvent, Charlotte Chabaud, Emilien Etienne, Hervé Kovacic, Bruno Guigliarelli, Vincent Peyrot, Isabelle Landrieu, Valérie Belle, Pascale Barbier.
Two Tau binding sites on tubulin revealed by thiol-disulfide exchanges.
Sci Rep, 2018, 8:13846, 1 - 11.
DOI: 10.1038/s41598-018-32096-9
HAL: hal-01883844v1
Angeliki M. Andrianaki, Irene Kyrmizi, Kalliopi Thanopoulou, Clara Baldin, Elias Drakos, Sameh S. M. Soliman, Amol C. Shetty, Carrie McCracken, Tonia Akoumianaki, Kostas Stylianou, Petros Ioannou, Charalampos Pontikoglou, Helen A. Papadaki, Maria Tzardi, Valerie Belle, Emilien Etienne, Anne Beauvais, George Samonis, Dimitrios P. Kontoyiannis, Evangelos Andreakos, Vincent M. Bruno, Ashraf S. Ibrahim, Georgios Chamilos.
Iron restriction inside macrophages regulates pulmonary host defense against Rhizopus species.
Nat Commun, 2018, 11 (Suppl. 1), R106.
DOI: 10.1038/s41467-018-05820-2
HAL: hal-01892640v1
Charles Gauquelin, Carole Baffert, Pierre Richaud, Emma Kamionka, Emilien Etienne, David Guieysse, Laurence Girbal, Vincent Fourmond, Isabelle André, Bruno Guigliarelli, Christophe Léger, Philippe Soucaille, Isabelle Meynial-Salles.
Roles of the F-domain in [FeFe] hydrogenase.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2018, 1859 (2), 69 - 77.
DOI: 10.1016/j.bbabio.2017.08.010
HAL: cea-01950818
2017
Marta Palombo, Alessio Bonucci, Emilien Etienne, Stefano Ciurli, Vladimir N. Uversky, Bruno Guigliarelli, Valérie Belle, Elisabetta Mileo, Barbara Zambelli.
The relationship between folding and activity in UreG, an intrinsically disordered enzyme.
Sci Rep, 2017, 89 (1), 392.
DOI: 10.1038/s41598-017-06330-9
HAL: hal-01585289v1
Emilien Etienne, Nolwenn Le Breton, Marlène Martinho, Elisabetta Mileo, Valérie Belle.
SimLabel: a graphical user interface to simulate continuous wave EPR spectra from site-directed spin labeling experiments.
Magn. Reson. Chem., 2017, 55 (8), 714 - 719.
DOI: 10.1002/mrc.4578
HAL: hal-01444172v1
2016
Pierre Ceccaldi, Emilien Etienne, Sébastien Dementin, Bruno Guigliarelli, Christophe Léger, Bénédicte Burlat.
Mechanism of inhibition of NiFe hydrogenase by nitric oxide.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2016, 1857 (4), 454 - 461.
DOI: 10.1016/j.bbabio.2016.01.014
HAL: hal-01413192v1
Nolwenn Le Breton, Tiona Adrianaivomananjaona, Guillaume Gerbaud, Emilien Etienne, Elena Bisetto, Alain Dautant, Bruno Guigliarelli, Francis Haraux, Marlène Martinho, Valérie Belle.
Dimerization interface and dynamic properties of yeast IF1 revealed by Site-Directed Spin Labeling EPR spectroscopy.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2016, 1857 (1), 89 - 97.
DOI: 10.1016/j.bbabio.2015.10.010
HAL: hal-01413333v1
2015
Jeremy Guérin, Nathalie Saint, Catherine Baud, Albano C. Meli, Emilien Etienne, Camille Locht, Hervé Vezin, Françoise Jacob-Dubuisson.
Dynamic interplay of membrane-proximal POTRA domain and conserved loop L6 in Omp85 transporter FhaC.
Molecular Microbiology, 2015, 98 (3), 490 - 501.
DOI: 10.1111/mmi.13137
HAL: hal-01432130v1
Nolwenn Le Breton, Marlène Martinho, Elisabetta Mileo, Emilien Etienne, Guillaume Gerbaud, Bruno Guigliarelli, Valérie Belle.
Exploring intrinsically disordered proteins using site-directed spin labeling electron paramagnetic resonance spectroscopy.
Front. Mol. Biosci., 2015, 2:21, 1 - 7.
DOI: 10.3389/fmolb.2015.00021
HAL: hal-01429982v1
2014
Julien G.J. Jacques, Vincent Fourmond, Pascal Arnoux, Monique Sabaty, Emilien Etienne, Sandrine Grosse, Frédéric Biaso, Patrick Bertrand, David Pignol, Christophe Léger, Bruno Guigliarelli, Bénédicte Burlat.
Reductive activation in periplasmic nitrate reductase involves chemical modifications of the Mo-cofactor beyond the first coordination sphere of the metal ion.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2014, 1837 (2), 277 - 286.
DOI: 10.1016/j.bbabio.2013.10.013
HAL: hal-01481487v1
2013
Elisabetta Mileo, Emilien Etienne, Marlène Martinho, Régine Lebrun, Valérie Roubaud, Paul Tordo, Brigitte Gontero, Bruno Guigliarelli, Sylvain R. A. Marque, Valérie Belle.
Enlarging the Panoply of Site-Directed Spin Labeling Electron Paramagnetic Resonance (SDSL-EPR): Sensitive and Selective Spin-Labeling of Tyrosine Using an Isoindoline-Based Nitroxide.
Bioconjugate Chem., 2013, 24 (6), 1110 - 1117.
DOI: 10.1021/bc4000542
HAL: hal-01460460v1
Elisabetta Mileo, Magali Lorenzi, Jenny Erales, Sabrina Lignon, Carine Puppo, Nolwenn Le Breton, Emilien Etienne, Sylvain R. A. Marque, Bruno Guigliarelli, Brigitte Gontero, Valérie Belle.
Dynamics of the intrinsically disordered protein CP12 in its association with GAPDH in the green alga Chlamydomonas reinhardtii: a fuzzy complex.
Mol. BioSyst., 2013, 1 (11), 349.
DOI: 10.1039/c3mb70190e
HAL: hal-01460463v1
2011
Carole Baffert, Luca Bertini, Thomas Lautier, Claudio Greco, Kateryna Sybirna, Pierre Ezanno, Emilien Etienne, Philippe Soucaille, Patrick Bertrand, Hervé Bottin, Isabelle Meynial-Salles, Luca De Gioia, Christophe Léger.
CO Disrupts the Reduced H-Cluster of FeFe Hydrogenase. A Combined DFT and Protein Film Voltammetry Study.
J. Am. Chem. Soc., 2011, 133 (7), 2096 - 2099.
DOI: 10.1021/ja110627b
HAL: hal-02652182v1
2010
Vincent Fourmond, Bénédicte Burlat, Sébastien Dementin, Monique Sabaty, Pascal Arnoux, Émilien Étienne, Bruno Guigliarelli, Patrick Bertrand, David Pignol, Christophe Léger.
Dependence of Catalytic Activity on Driving Force in Solution Assays and Protein Film Voltammetry: Insights from the Comparison of Nitrate Reductase Mutants.
Biochemistry, 2010, 49 (11), 2424 - 2432.
DOI: 10.1021/bi902140e
HAL: hal-00677461
2009
Jenny Erales, Magali Lorenzi, Régine Lebrun, André Fournel, Emilien Etienne, Carine Courcelle, Bruno Guigliarelli, Brigitte Gontero, Valérie Belle.
A New Function of GAPDH from Chlamydomonas reinhardtii: A Thiol−Disulfide Exchange Reaction with CP12.
Biochemistry, 2009, 48 (25), 6034 - 6040.
DOI: 10.1021/bi900569h
HAL: hal-00429826