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Directeur de Recherche, CNRS

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Frédéric Carrière, PhD, is Research Director at Centre National de la Recherche Scientifique (CNRS) and he currently works in the group of Enzymology of Supramolecular Systems at the Bioenergetics and Protein Engineering laboratory of CNRS and Aix Marseille University, Marseille, France. Over the last 30 years, his main research activities have been dealing with the biochemistry of lipids and lipolytic enzymes, with a strong interest in methods for studying lipid-protein interactions at interfaces and for lipolytic enzyme assays. Besides these molecular aspects based on protein engineering, biophysical methods and analytical chemistry, he investigated lipid digestion both in vitro and in vivo in the course of clinical studies. He has contributed to a better understanding of the relative contributions to lipid digestion of several enzymes, including gastric lipase, pancreatic lipase and pancreatic lipase-related protein 2. His studies have paid the way to the development of in vitro digestion methods, of lipase inhibitors for obesity treatment and of lipases for enzyme replacement therapy in patients with exocrine pancreatic insufficiency.
He is the author of >200 publications (h-index >46; see Researchgate ; ResearcherID: E-8408-2010; Google scholar ; ORCID ). Among other duties, Frédéric Carrière has been Unit Director of the laboratory of Enzymology at Interfaces and Physiology of Lipolysis (CNRS, Aix-Marseille University) from 2004 to 2017, Scientific Director of the LISA Carnot Institute (Lipids for Health and Industry), a consortium of laboratories aiming at partnership with industry in the field of lipid science and technology, from 2009 to 2015. He was president of GERLI (Groupe d’Etude et de Recherche en Lipidomique, the lipid section of the French Society for Biochemistry and Molecular Biology) from 2008 to 2014 and he is still a member of GERLI scientific board. Since 2007, he is a member of the Biologics Expert Committee at United States Pharmacopeia and Chair of the Pharmaceutical Enzyme Panel. Prior to join CNRS, he was employed as a researcher by the Jouveinal Laboratories (1988-1992; CIFRE contract)and Novo Nordisk A/S in Denmark(1992-1994). He was awarded the Chevreul medal in 2007 for his work on lipid science.

ORCID id: 0000-0003-4848-9418


Sawsan Amara, Jérôme Lecomte, Nathalie Barouh, Moulay Sahaka, Dominique Lafont, Jean-David Rodier, Goetz Parsiegla, Frédéric Demarne, Brigitte Gontero, Pierre Villeneuve, Frédéric Carrière.
Using Enzymes to Harvest Fatty Acids from Galactosyldiacylglycerols, the Most Abundant Lipids in Plant Biomass.
ACS Sustainable Chem. Eng., 2024, - . DOI: 10.1021/acssuschemeng.3c07439 HAL: hal-04484899

Moulay Sahaka, Olivier Bornet, Achille Marchand, Dominique Lafont, Brigitte Gontero, Frédéric Carrière, Hélène Launay.
Monitoring galactolipid digestion and simultaneous changes in lipid-bile salt micellar organization by real-time NMR spectroscopy.
Chemistry and Physics of Lipids, 2024, 258, 105361 - . DOI: 10.1016/j.chemphyslip.2023.105361 HAL: hal-04306594


Gérard Lambeau, Ez-Zoubir Amri, Frédéric Carrière.
Lipids play music at the cellular membrane: From membranes dynamics to signaling via lipid mediators, vesicles and lipid droplets.
Biochimie, 2023, 215, 1 - 3. DOI: 10.1016/j.biochi.2023.11.002 HAL: hal-04396068

Hélène Launay, Luisana Avilan, Cassy Gérard, Goetz Parsiegla, Véronique Receveur‐Brechot, Brigitte Gontero, Frédéric Carriere.
Location of the photosynthetic carbon metabolism in microcompartments and separated phases in microalgal cells.
FEBS Letters, 2023, - . DOI: 10.1002/1873-3468.14754 HAL: hal-04290010v1

Marcos R. Infantes-Garcia, Sarah H.E. Verkempinck, Fréderic Carriére, Marc E. Hendrickx, Tara Grauwet.
Pre-duodenal lipid digestion of emulsions: Relevance, colloidal aspects and mechanistic insight.
Food Research International, 2023, 168, 112785. DOI: 10.1016/j.foodres.2023.112785 HAL: hal-04061615

O. Menard, U. Lesmes, C. S. Shani-Levi, A. Araiza Calahorra, A. Lavoisier, M. Morzel, A. Rieder, G. Feron, S. Nebbia, L. Mashiah, A. Andres, G. Bornhorst, F. Carrière, L. Egger, S. Gwala, A. Heredia, B. Kirkhus, A. Macierzanka, R. Portman, I. Recio, V. Santé-Lhoutellier, C. Tournier, A. Sarkar, A. Brodkorb, A. Mackie, D. Dupont.
Static in vitro digestion model adapted to the general older adult population: an INFOGEST international consensus.
Food Funct., 2023, 14, 4569-4582. DOI: 10.1039/D3FO00535F HAL: hal-04093864

Jeanne Kergomard, Frédéric Carrière, Gilles Paboeuf, Lauriane Chonchon, Nathalie Barouh, Véronique Vié, Claire Bourlieu.
Interfacial adsorption and activity of pancreatic lipase-related protein 2 onto heterogeneous plant lipid model membrane.
Biochimie, 2023. DOI: 10.1016/j.biochi.2023.04.001 HAL: hal-04070337

Moulay Sahaka, Eduardo Mateos-Diaz, Sawsan Amara, Jutarat Wattanakul, David Gray, Dominique Lafont, Brigitte Gontero, Hélène Launay, Frédéric Carrière.
In situ monitoring of galactolipid digestion by infrared spectroscopy in both model micelles and spinach chloroplasts.
Chemistry and Physics of Lipids, 2023, 252, 105291. DOI: 10.1016/j.chemphyslip.2023.105291 HAL: hal-04028212

Jeanne Kergomard, Frédéric Carrière, Nathalie Barouh, Pierre Villeneuve, Véronique Vié, Claire Bourlieu.
Digestibility and oxidative stability of plant lipid assemblies: An underexplored source of potentially bioactive surfactants?.
Critical Reviews in Food Science and Nutrition, 2023, 1 - 20. DOI: 10.1080/10408398.2021.2005532 HAL: hal-03464523v1


Jeanne Kergomard, Frédéric Carrière, Gilles Paboeuf, Nathalie Barouh, Claire Bourlieu-Lacanal, Véronique Vié.
Modulation of gastric lipase adsorption onto mixed galactolipid-phospholipid films by addition of phytosterols.
Colloids and Surfaces B: Biointerfaces, 2022, 220, 112933 -. DOI: 10.1016/j.colsurfb.2022.112933 HAL: hal-03822328v2

Jeanne Kergomard, Frédéric Carrière, Gilles Paboeuf, Franck Artzner, Nathalie Barouh, Claire Bourlieu, Véronique Vié.
Interfacial organization and phase behavior of mixed galactolipid-DPPC-phytosterol assemblies at the air-water interface and in hydrated mesophases.
Colloids and Surfaces B: Biointerfaces, 2022, 217, 112646 -. DOI: 10.1016/j.colsurfb.2022.112646 HAL: hal-03702655v1

Cassy Gérard, Frédéric Carrière, Véronique Receveur-Bréchot, Hélène Launay, Brigitte Gontero.
A Trajectory of Discovery: Metabolic Regulation by the Conditionally Disordered Chloroplast Protein, CP12.
Biomolecules, 2022, 12 (8), 1047 -. DOI: 10.3390/biom12081047 HAL: hal-03747280

Cassy Gérard, Régine Lebrun, Erwan Lemesle, Luisana Avilan, Kwang Suk Chang, EonSeon Jin, Frédéric Carrière, Brigitte Gontero, Hélène Launay.
Reduction in Phosphoribulokinase Amount and Re-Routing Metabolism in Chlamydomonas reinhardtii CP12 Mutants.
IJMS, 2022, 23 (5), 2710 -. DOI: 10.3390/ijms23052710 HAL: hal-03594470

Jutarat Wattanakul, Mansor Syamila, Randa Darwish, Mohamed A. Gedi, Poramat Sutcharit, Chao Chi, Patchaniya Akepach, Moulay Sahaka, Brigitte Gontero, Frédéric Carrière, David A. Gray.
Bioaccessibility of essential lipophilic nutrients in a chloroplast-rich fraction (CRF) from agricultural green waste during simulated human gastrointestinal tract digestion.
Food Funct., 2022. DOI: 10.1039/D2FO00604A HAL: hal-03653719v1


Emna Moujehed, Zied Zarai, Haifa Khemir, Neila Miled, Mohamed Salah Bchir, Corinne Gablin, François Bessueille, Anne Bonhommé, Didier Leonard, Frédéric Carrière, Ahmed Aloulou.
Cleaner degreasing of sheepskins by the Yarrowia lipolytica LIP2 lipase as a chemical-free alternative in leather industry.
Colloids and Surfaces B: Biointerfaces, 2021, 112292 -. DOI: 10.1016/j.colsurfb.2021.112292 HAL: hal-03494701

Cyril Aselmeyer, Bertrand Légeret, Anaïs Bénarouche, Damien Sorigué, Goetz Parsiegla, Fred Beisson, Frédéric Carrière.
Fatty Acid Photodecarboxylase Is an Interfacial Enzyme That Binds to Lipid–Water Interfaces to Access Its Insoluble Substrate.
Biochemistry, 2021, 60 (42), 3200 - 3212. DOI: 10.1021/acs.biochem.1c00317 HAL: hal-03381197v1

Hélène Launay, Véronique Receveur-Bréchot, Frédéric Carrière, Brigitte Gontero.
Protein disorder in algal metabolism.
Atlas of Science, 2021. (voir / see) HAL: hal-03326941

Myriam M.L. Grundy, Evan Abrahamse, Annette Almgren, Marie Alminger, Ana Andres, Renata M.C. Ariëns, Shanna Bastiaan-Net, Claire Bourlieu-Lacanal, André Brodkorb, Maria R. Bronze, Irene Comi, Leslie Couëdelo, Didier Dupont, Annie Durand, Sedef N. El, Tara Grauwet, Christine Heerup, Ana Heredia, Marcos R. Infantes Garcia, Christian Jungnickel, Ilona E. Kłosowska-Chomiczewska, Marion Létisse, Adam Macierzanka, Alan R. Mackie, David J. McClements, Olivia Menard, Anne Meynier, Marie-Caroline Michalski, Ana-Isabel Mulet-Cabero, Anette Mullertz, Francina M. Payeras Perelló, Irene Peinado, Mélina Robert, Sébastien Secouard, Ana T. Serra, Sandra D. Silva, Gabriel Thomassen, Cecilia Tullberg, Ingrid Undeland, Carole Vaysse, Gerd E. Vegarud, Sarah H.E. Verkempinck, Michelle Viau, Mostafa Zahir, Ruojie Zhang, Frédéric Carrière.
INFOGEST inter-laboratory recommendations for assaying gastric and pancreatic lipases activities prior to in vitro digestion studies.
Journal of Functional Foods, 2021, 82, 104497 -. DOI: 10.1016/j.jff.2021.104497 HAL: hal-03224818v1

Tiffany Antoine, Christèle Icard-Vernière, Giulia Scorrano, Amal Salhi, Charlotte Halimi, Stéphane Georgé, Frédéric Carrière, Claire Mouquet-Rivier, Emmanuelle Reboul.
Evaluation of vitamin D bioaccessibility and mineral solubility from test meals containing meat and/or cereals and/or pulses using in vitro digestion.
Food Chemistry, 2021, 347, 128621 -. DOI: 10.1016/j.foodchem.2020.128621 HAL: hal-03146299v1

Moulay Sahaka, Sawsan Amara, Jérôme Lecomte, Jean-David Rodier, Dominique Lafont, Pierre Villeneuve, Brigitte Gontero, Frédéric Carrière.
Quantitative monitoring of galactolipid hydrolysis by pancreatic lipase-related protein 2 using thin layer chromatography and thymol-sulfuric acid derivatization.
Journal of Chromatography B, 2021, 1173, 122674 -. DOI: 10.1016/j.jchromb.2021.122674 HAL: hal-03191084v1

A. Salhi, F. Carriere, Myriam M. -L. Grundy, A. Aloulou.
Enzymes involved in lipid digestion.
Bioaccessibility and Digestibility of Lipids from Food, 2021, 3 - 28. DOI: 10.1007/978-3-030-56909-9_1 HAL: hal-03146298v1

Erwann Durand, Pierre Villeneuve, Claire Bourlieu-lacanal, Frédéric Carrière.
Natural Deep Eutectic Solvents: hypothesis for their possible roles in cellular functions and interaction with membranes and other organized biological systems.
Adv Bot Res, 2021, 97, 133 - 158. DOI: 10.1016/bs.abr.2020.09.005 HAL: hal-02965391v1


Milena Chagas Lisboa, Flávia Michelle Silva Wiltshire, Alini Tinoco Fricks, Claudio Dariva, Frédéric Carrière, Álvaro Silva Lima, Cleide Mara Faria Soares.
Oleochemistry potential from Brazil northeastern exotic plants.
Biochimie, 2020, 178, 96 - 104. DOI: 10.1016/j.biochi.2020.09.002 HAL: hal-02946034v1

Sue Yee Lim, Panagiotis G. Xenoulis, Evangelia M. Stavroulaki, Jonathan A. Lidbury, Jan S. Suchodolski, Frédéric Carrière, Jörg M. Steiner.
The 1,2‐o‐dilauryl‐rac‐glycero‐3‐glutaric acid‐(6’‐methylresorufin) ester (DGGR) lipase assay in cats and dogs is not specific for pancreatic lipase.
Vet Clin Pathol, 2020, 49 (4), 607 - 613. DOI: 10.1111/vcp.12906 HAL: hal-02983429v1

Frédéric Carrière, Sonia Longhi, Michel Record.
The endosomal lipid bis(monoacylglycero) phosphate as a potential key player in the mechanism of action of chloroquine against SARS-COV-2 and other enveloped viruses hijacking the endocytic pathway.
Biochimie, 2020. DOI: 10.1016/j.biochi.2020.05.013 HAL: hal-02693984v1

Yonghua Li-Beisson, Frédéric Carrière.
Biogenesis and fate of lipid droplets.
Biochimie, 2020, 169, 1 - 2. DOI: 10.1016/j.biochi.2020.01.001 HAL: hal-02904326v1

Amal Salhi, Sawsan Amara, Pascal Mansuelle, Rémy Puppo, Régine Lebrun, Brigitte Gontero, Ahmed Aloulou, Frédéric Carrière.
Characterization of all the lipolytic activities in pancreatin and comparison with porcine and human pancreatic juices.
Biochimie, 2020, 169, 106 - 120. DOI: 10.1016/j.biochi.2019.07.004 HAL: hal-02265768v1

Claire Bourlieu, Wafa Mahdoueni, Gilles Paboeuf, Eric Gicquel, Olivia Ménard, Stéphane Pezennec, Said Bouhallab, Amélie Deglaire, Didier Dupont, Frédéric Carrière, Véronique Vié.
Physico-chemical behaviors of human and bovine milk membrane extracts and their influence on gastric lipase adsorption.
Biochimie, 2020, 169, 95 - 105. DOI: 10.1016/j.biochi.2019.12.003 HAL: hal-02444026v1

Laura Prioretti, Frédéric Carriere, Ben Field, Luisana Avilan, Marie-Hélène Montané, Benoît Menand, Brigitte Gontero.
Targeting TOR signaling for enhanced lipid productivity in algae.
Biochimie, 2020, 169, 12 - 17. DOI: 10.1016/j.biochi.2019.06.016 HAL: hal-02129344v1

Ana-Isabel Mulet-Cabero, Lotti Egger, Reto Portmann, Olivia Ménard, Sébastien Marze, Mans Minekus, Steven Le Feunteun, Anwesha Sarkar, Myriam M.-L. Grundy, Frédéric Carrière, Matt Golding, Didier Dupont, Isidra Recio, André Brodkorb, Alan Mackie.
A standardised semi-dynamic in vitro digestion method suitable for food – an international consensus.
Food Funct., 2020, 11 (2), 1702 - 1720. DOI: 10.1039/c9fo01293a HAL: hal-02648755v1

Slim Cherif, Frederic Carrière, Adel Sayari, Ahmed Fendri.
Studies of crab digestive phospholipase acting on phospholipid monolayers: Activation by temperature.
International Journal of Biological Macromolecules, 2020, 142, 705 - 711. DOI: 10.1016/j.ijbiomac.2019.10.011 HAL: hal-02326884v1

Moulay Sahaka, Sawsan Amara, Jutarat Wattanakul, Mohamed A. Gedi, Noelia Aldai, Goetz Parsiegla, Jérôme Lecomte, John T. Christeller, David Gray, Brigitte Gontero, Pierre Villeneuve, Frédéric Carrière.
The digestion of galactolipids and its ubiquitous function in Nature for the uptake of the essential α-linolenic acid.
Food Funct., 2020. DOI: 10.1039/D0FO01040E HAL: hal-02903683v1

Maria Angeles Camacho-Ruiz, Enrique Ordaz, Manuel R. Kirchmayr, Hugo Esquivel-Solís, Ali Asaff-Torres, Juan Carlos Mateos-Díaz, Frédéric Carriѐre, Jorge A. Rodríguez.
Screening of Gastrointestinal Lipase Inhibitors Produced by Microorganisms Isolated from Soil and Lake Sediments.
Int Microbiol, 2020, 23 (2), 335 - 343. DOI: 10.1007/s10123-019-00107-y HAL: hal-02904324v1


Erik L. Jensen, Karen Yangüez, Frédéric Carrière, Brigitte Gontero.
Storage Compound Accumulation in Diatoms as Response to Elevated CO2 Concentration.
Biology, 2019, 25 (1), 1266 -. DOI: 10.3390/biology9010005 HAL: hal-02431926v1

Sabine Danthine, Cécile Vors, Damien Agopian, Annie Durand, Romain Guyon, Frédéric Carriere, Carole Knibbe, Marion Létisse, Marie-Caroline Michalski.
Homogeneous triacylglycerol tracers have an impact on the thermal and structural properties of dietary fat and its lipolysis rate under simulated physiological conditions.
Chemistry and Physics of Lipids, 2019, 225, 104815 -. DOI: 10.1016/j.chemphyslip.2019.104815 HAL: hal-02326893v1

Hélène Launay, Véronique Receveur-Bréchot, Frédéric Carrière, Brigitte Gontero.
Orchestration of algal metabolism by protein disorder.
Archives of Biochemistry and Biophysics, 2019, 672, 108070 -. DOI: 10.1016/ HAL: hal-02266032v1

André Brodkorb, Lotti Egger, Marie Alminger, Paula Alvito, Ricardo Assunção, Simon Ballance, Torsten Bohn, Claire Bourlieu-Lacanal, Rachel Boutrou, Frédéric Carrière, Alfonso Clemente, Milena Corredig, Didier Dupont, Claire Dufour, Cathrina Edwards, Matt Golding, Sibel Karakaya, Bente Kirkhus, Steven Le Feunteun, Uri Lesmes, Adam Macierzanka, Alan R. Mackie, Carla Martins, Sébastien Marze, David Julian McClements, Olivia Ménard, Mans Minekus, Reto Portmann, Cláudia N. Santos, Isabelle Souchon, R. Paul Singh, Gerd E. Vegarud, Martin S. J. Wickham, Werner Weitschies, Isidra Recio.
INFOGEST static in vitro simulation of gastrointestinal food digestion.
Nat Protoc, 2019, 14 (4), 991 - 1014. DOI: 10.1038/s41596-018-0119-1 HAL: hal-02073386v1

Sawsan Amara, Claire Bourlieu, Lydie Humbert, Dominique Rainteau, Frédéric Carrière.
Variations in gastrointestinal lipases, pH and bile acid levels with food intake, age and diseases: Possible impact on oral lipid-based drug delivery systems.
Advanced Drug Delivery Reviews, 2019, 142, 3 - 15. DOI: 10.1016/j.addr.2019.03.005 HAL: hal-02326907v1

Jeske H. J. Hageman, Jaap Keijer, Trine Kastrup Dalsgaard, Lara W. Zeper, Frédéric Carrière, Anouk L. Feitsma, Arie G. Nieuwenhuizen.
Free fatty acid release from vegetable and bovine milk fat-based infant formulas and human milk during two-phase in vitro digestion.
Food Funct., 2019, 10 (4), 2102 - 2113. DOI: 10.1039/c8fo01940a HAL: hal-02326910v1

Jannet Kamoun, Renaud Rahier, Mohamed Sellami, Imed Koubaa, Pascal Mansuelle, Régine Lebrun, Alexandra Berlioz-Barbier, Michele Fiore, Karine Alvarez, Abdelkarim Abousalham, Frédéric Carrière, Ahmed Aloulou.
Identification of a new natural gastric lipase inhibitor from star anise.
Food Funct., 2019, 10 (1), 469 - 478. DOI: 10.1039/c8fo02009d HAL: hal-03006544v1

Jutarat Wattanakul, Moulay Sahaka, Sawsan Amara, Syamila Mansor, Brigitte Gontero, Frédéric Carrière, David Gray.
In vitro digestion of galactolipids from chloroplast-rich fraction (CRF) of postharvest, pea vine field residue (haulm) and spinach leaves.
Food Funct., 2019, 1760 (1), 1497 - 7817. DOI: 10.1039/c9fo01867k HAL: hal-02431885v1


Lydie Humbert, Dominique Rainteau, Noshine Tuvignon, Claude Wolf, Philippe Seksik, René Laugier, Frédéric Carrière.
Postprandial bile acid levels in intestine and plasma reveal altered biliary circulation in chronic pancreatitis patients.
J. Lipid Res., 2018, 1801 (11), 665 - 2213. DOI: 10.1194/jlr.M084830 HAL: hal-01990491v1

Inès Belhaj, Sawsan Amara, Goetz Parsiegla, Priscila Sutto-Ortiz, Moulay Sahaka, Hafedh Belghith, Audric Rousset, Dominique Lafont, Frédéric Carrière.
Galactolipase activity of Talaromyces thermophilus lipase on galactolipid micelles, monomolecular films and UV-absorbing surface-coated substrate.
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2018, 1863 (9), 1006 - 1015. DOI: 10.1016/j.bbalip.2018.05.016 HAL: hal-01819569v1

Claire Bourlieu, Amélie Deglaire, Samira Cassia de Oliveira, Olivier Ménard, Yann Le Gouar, Frédéric Carrière, Didier Dupont.
Vers des formules infantiles biomimétiques de la structure du lait maternel et de son comportement digestif ?.
Cahiers de Nutrition et de Diététique, 2018, 53 (4), 218 - 231. DOI: 10.1016/j.cnd.2017.12.002 HAL: hal-02943584v1

Najeh Krayem, Goetz Parsiegla, Hélène Gaussier, Hanen Louati, Raida Jallouli, Pascal Mansuelle, Frédéric Carrière, Youssef Gargouri.
Functional characterization and FTIR-based 3D modeling of full length and truncated forms of Scorpio maurus venom phospholipase A 2.
Biochimica et Biophysica Acta (BBA) - General Subjects, 2018, 1862 (5), 1247 - 1261. DOI: 10.1016/j.bbagen.2018.02.004 HAL: hal-01739569v1

Eduardo Mateos-Diaz, Jean-Claude Bakala N’Goma, Deborah Byrne, Sylvie Robert, Frédéric Carrière, Hélène Gaussier.
IR spectroscopy analysis of pancreatic lipase-related protein 2 interaction with phospholipids: 1. Discriminative recognition of mixed micelles versus liposomes.
Chemistry and Physics of Lipids, 2018, 211, 52 - 65. DOI: 10.1016/j.chemphyslip.2017.02.005 HAL: hal-02325970v1

Eduardo Mateos-Diaz, Priscila Sutto-Ortiz, Moulay Sahaka, Deborah Byrne, Hélène Gaussier, Frédéric Carrière.
IR spectroscopy analysis of pancreatic lipase-related protein 2 interaction with phospholipids: 2. Discriminative recognition of various micellar systems and characterization of PLRP2-DPPC-bile salt complexes.
Chemistry and Physics of Lipids, 2018, 211, 66 - 76. DOI: 10.1016/j.chemphyslip.2017.11.012 HAL: hal-02325977v1

Eduardo Mateos-Diaz, Priscila Sutto-Ortiz, Moulay Sahaka, Jorge A. Rodriguez, Frédéric Carrière.
IR spectroscopy analysis of pancreatic lipase-related protein 2 interaction with phospholipids: 3. Monitoring DPPC lipolysis in mixed micelles.
Chemistry and Physics of Lipids, 2018, 211, 77 - 85. DOI: 10.1016/j.chemphyslip.2017.11.009 HAL: hal-02325989v1

Mirko Koziolek, Frédéric Carrière, Christopher J. H. Porter.
Lipids in the Stomach – Implications for the Evaluation of Food Effects on Oral Drug Absorption.
Pharm Res, 2018, 35 (3). DOI: 10.1007/s11095-017-2289-x HAL: hal-02325961v1

O. Ménard, C. Bourlieu, S.C. De Oliveira, N. Dellarosa, L. Laghi, F. Carrière, F. Capozzi, D. Dupont, A. Deglaire.
A first step towards a consensus static in vitro model for simulating full-term infant digestion.
Food Chemistry, 2018, 240, 338 - 345. DOI: 10.1016/j.foodchem.2017.07.145 HAL: hal-01769298v1

Laura Sams, Sawsan Amara, Pascal Mansuelle, Rémy Puppo, Régine Lebrun, Julie Paume, Jacqueline Giallo, Frédéric Carrière.
Characterization of pepsin from rabbit gastric extract, its action on β-casein and the effects of lipids on proteolysis.
Food Funct., 2018, 9 (11), 5975 - 5988. DOI: 10.1039/c8fo01450g HAL: hal-02325924v1


Laura Prioretti, Luisana Avilan, Frédéric Carrière, Marie-Hélène Montané, Ben Field, Gérald Grégori, Benoît Menand, Brigitte Gontero.
The inhibition of TOR in the model diatom Phaeodactylum tricornutum promotes a get-fat growth regime.
Algal Research, 2017, 26, 265 - 274. DOI: 10.1016/j.algal.2017.08.009 HAL: hal-01696878v1

Raida Jallouli, Goetz Parsiegla, Frédéric Carrière, Youssef Gargouri, Sofiane Bezzine.
Efficient heterologous expression of Fusarium solani lipase, FSL2, in Pichia pastoris, functional characterization of the recombinant enzyme and molecular modeling.
International Journal of Biological Macromolecules, 2017, 94, 61 - 71. DOI: 10.1016/j.ijbiomac.2016.09.030


Raida Jallouli, Houcemeddine Othman, Sawsan Amara, Goetz Parsiegla, Frédéric Carriere, Najet Srairi-abid, Youssef Gargouri, Sofiane Bezzine.
The galactolipase activity of Fusarium solani (phospho)lipase.
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2015, 1851 (3), 282 - 289. DOI: 10.1016/j.bbalip.2014.12.010

Jannet Kamoun, Mathieu Schué, Wala Messaoud, Justine Baignol, Vanessa Point, Eduardo Mateos-Diaz, Pascal Mansuelle, Youssef Gargouri, Goetz Parsiegla, Jean-François Cavalier, Frédéric Carrière, Ahmed Aloulou.
Biochemical characterization of Yarrowia lipolytica LIP8, a secreted lipase with a cleavable C-terminal region.
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2015, 1851 (2), 129 - 140. DOI: 10.1016/j.bbalip.2014.10.012


Malika Mekhalfi, Sawsan Amara, Sylvie Robert, Frédéric Carrière, Brigitte Gontero.
Effect of environmental conditions on various enzyme activities and triacylglycerol contents in cultures of the freshwater diatom, Asterionella formosa (Bacillariophyceae).
Biochimie, 2014, 101, 21 - 30. DOI: 10.1016/j.biochi.2013.12.004 HAL: hal-02165163v1


Anaïs Bénarouche, Vanessa Point, Goetz Parsiegla, Frédéric Carrière, Jean-François Cavalier.
New insights into the pH-dependent interfacial adsorption of dog gastric lipase using the monolayer technique.
Colloids and Surfaces B: Biointerfaces, 2013, 111, 306 - 312. DOI: 10.1016/j.colsurfb.2013.06.025

Sawsan Amara, Dominique Lafont, Goetz Parsiegla, Vanessa Point, Aurélie Chabannes, Audric Rousset, Frédéric Carrière.
The galactolipase activity of some microbial lipases and pancreatic enzymes.
Eur. J. Lipid Sci. Technol., 2013, 1771 (4), 1446 - 451. DOI: 10.1002/ejlt.201300004

Vanessa Point, Anaïs Bénarouche, Ikram Jemel, Goetz Parsiegla, Gérard Lambeau, Frédéric Carrière, Jean-François Cavalier.
Effects of the propeptide of group X secreted phospholipase A2 on substrate specificity and interfacial activity on phospholipid monolayers.
Biochimie, 2013, 95 (1), 51 - 58. DOI: 10.1016/j.biochi.2012.07.023


Vanessa Point, K.V.P. Pavan Kumar, Sylvain Marc, Vincent Delorme, Goetz Parsiegla, Sawsan Amara, Frédéric Carrière, Gérard Buono, Frédéric Fotiadu, Stéphane Canaan, Julien Leclaire, Jean-François Cavalier.
Analysis of the discriminative inhibition of mammalian digestive lipases by 3-phenyl substituted 1,3,4-oxadiazol-2(3H)-ones.
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Goetz Parsiegla, Bindesh Shrestha, Frédéric Carrière, Akos Vertes.
Direct Analysis of Phycobilisomal Antenna Proteins and Metabolites in Small Cyanobacterial Populations by Laser Ablation Electrospray Ionization Mass Spectrometry.
Anal. Chem., 2012, 84 (1), 34 - 38. DOI: 10.1021/ac202831w


Sonia Longhi, Valérie Belle, André Fournel, Bruno Guigliarelli, Frédéric Carrière.
Probing structural transitions in both structured and disordered proteins using site-directed spin-labeling EPR spectroscopy.
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