Guillaume GERBAUD

member photo

Ingénieur de Recherche, CNRS

+33 4 91 16 44 65

Equipe / Group: BIP 07



Maxime Bizet, Deborah Byrne, Frédéric Biaso, Guillaume Gerbaud, Emilien Etienne, Giuseppina Briola, Bruno Guigliarelli, Philippe Urban, Pierre Dorlet, Tamas Kalai, Gilles Truan, Marlene Martinho.
Structural insights into the semiquinone form of human Cytochrome P450 reductase by DEER distance measurements between a native flavin and a spin labelled non‐canonical amino acid.
Chemistry Eur J, 2024. DOI: 10.1002/chem.202304307 HAL: hal-04426634

Xavier Kubiak, Ivan Polsinelli, Leonard M. G. Chavas, Cameron D. Fyfe, Alain Guillot, Laura Fradale, Clémence Brewee, Stéphane Grimaldi, Guillaume Gerbaud, Aurélien Thureau, Pierre Legrand, Olivier Berteau, Alhosna Benjdia.
Structural and mechanistic basis for RiPP epimerization by a radical SAM enzyme.
Nat Chem Biol, 2024. DOI: 10.1038/s41589-023-01493-1 HAL: hal-04371487

Margot Di Cesare, Elise Kaplan, Julia Rendon, Guillaume Gerbaud, Sepideh Valimehr, Alexia Gobet, Thu-Anh Thi Ngo, Vincent Chaptal, Pierre Falson, Marlène Martinho, Pierre Dorlet, Eric Hanssen, Jean-Michel Jault, Cédric Orelle.
The transport activity of the multidrug ABC transporter BmrA does not require a wide separation of the nucleotide-binding domains.
Journal of Biological Chemistry, 2024, 300 (1), 105546. DOI: 10.1016/j.jbc.2023.105546 HAL: hal-04435310


Annalisa Pierro, Ketty Concetta Tamburrini, Hugo Leguenno, Guillaume Gerbaud, Emilien Etienne, Bruno Guigliarelli, Valérie Belle, Barbara Zambelli, Elisabetta Mileo.
In-cell investigation of the conformational landscape of the GTPase UreG by SDSL-EPR.
iScience, 2023, 26 (10), 107855. DOI: 10.1016/j.isci.2023.107855 HAL: hal-04233485v1

Guillaume Gerbaud, Brice Barbat, Mathilde Tribout, Emilien Etienne, Valérie Belle, Badreddine Douzi, Romé Voulhoux, Alessio Bonucci.
Refining the Dynamic Network of T2SS Endopilus Tip Heterocomplex Combining cw‐EPR and Nitroxide–Gd III Distance Measurements.
ChemBioChem, 2023, 24 (15), e2023000. DOI: 10.1002/cbic.202300099 HAL: hal-04210232v1

Pierre Nabokoff, Guillaume Brulay, Cyrielle Dol, Guillaume Gerbaud, Bruno Guigliarelli, Emilien Etienne, Emily Bloch, Fabio Ziarelli, Eric Besson, Stéphane Gastaldi.
Synthesis and Characterization of Face-to-Face Arylsulfanyl and Phenoxyl Radicals Embedded in Mesoporous Silicas.
J. Phys. Chem. C, 2023, 127 (20), 9699 - 9706. DOI: 10.1021/acs.jpcc.3c01550 HAL: hal-04114864v1

D. Marin, G. Gerbaud, O. Margeat, F. Ziarelli, F. Ferrer, O. Ouari, A. Campos, S. Bertaina, A. Savoyant.
Magnetic functionalization of ZnO nanoparticles surfaces via optically generated methyl radicals.
J. Chem. Phys., 2023, 158 (18). DOI: 10.1063/5.0152015 HAL: hal-04115234v1


Annalisa Pierro, Alessio Bonucci, Davide Normanno, Mireille Ansaldi, Eric Pilet, Olivier Ouari, Bruno Guigliarelli, Emilien Etienne, Guillaume Gerbaud, Axel Magalon, Valérie Belle, Elisabetta Mileo.
Probing Structural Dynamics of a Bacterial Chaperone in Its Native Environment by Nitroxide‐Based EPR Spectroscopy.
Chemistry A European J, 2022. DOI: 10.1002/chem.202202249 HAL: hal-03836431

Batoul Srour, Sylvain Gervason, Maren Hellen Hoock, Beata Monfort, Kristian Want, Djabir Larkem, Nadine Trabelsi, Gautier Landrot, Andrea Zitolo, Emiliano Fonda, Emilien Etienne, Guillaume Gerbaud, Christina Sophia Müller, Jonathan Oltmanns, Jesse B. Gordon, Vishal Yadav, Malgorzata Kleczewska, Marcin Jelen, Michel B. Toledano, Rafal Dutkiewicz, David P. Goldberg, Volker Schünemann, Bruno Guigliarelli, Bénédicte Burlat, Christina Sizun, Benoit D’Autréaux.
Iron Insertion at the Assembly Site of the ISCU Scaffold Protein Is a Conserved Process Initiating Fe–S Cluster Biosynthesis.
J. Am. Chem. Soc., 2022. DOI: 10.1021/jacs.2c06338 HAL: hal-03837292v1

Julia Rendon, Margot Di Cesare, Alexia Godet, Guillaume Gerbaud, Emilien Etienne, Vincent Chaptal, Pierre Falson, Jean-Michel Jault, Cédric Orelle, Marlène Martinho, Pierre Dorlet.
Conformational dynamics of the ABC-transporter BmrA reveals by SDSL-EPR spectroscopy.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2022, 1863. DOI: 10.1016/j.bbabio.2022.148732

Pierre Dorlet, Guillaume Gerbaud, Emilien Etienne, Stéphane Grimaldi, Bruno Guigliarelli, Valérie Belle.
EPR-MRS site: EPR spectroscopy for the study of biomolecules.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2022, 1863, Supplement, 29. DOI: 10.1016/j.bbabio.2022.148685 HAL: hal-03805551v1

Pierre Dorlet, Guillaume Gerbaud, Emilien Etienne, Stéphane Grimaldi, Bruno Guigliarelli, Valérie Belle.
MOSBRI- A New European Research Infrastructure for Molecular Biophysics.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2022, 1863, Supplement, 28. DOI: 10.1016/j.bbabio.2022.148684 HAL: hal-03805560v1

Eric Besson, Aurelien Vebr, Fabio Ziarelli, Emily Bloch, Guillaume Gerbaud, Séverine Queyroy, Pierre Thureau, Stéphane Viel, Stéphane Gastaldi.
Investigating the efficiency of silica materials with wall-embedded nitroxide radicals for dynamic nuclear polarisation NMR.
Phys. Chem. Chem. Phys., 2022, 24 (41), 25279 - 25286. DOI: 10.1039/d2cp02872g HAL: hal-03844800

Miguel Á. Casado-Combreras, Francisco Rivero-Rodríguez, Carlos A. Elena-Real, Dmitry Molodenskiy, Antonio Díaz-Quintana, Marlène Martinho, Guillaume Gerbaud, Katiuska González-Arzola, Adrián Velázquez-Campoy, Dmitri Svergun, Valérie Belle, Miguel A. De la Rosa, Irene Díaz-Moreno.
PP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ.
Computational and Structural Biotechnology Journal, 2022, 20, 3695 - 3707. DOI: 10.1016/j.csbj.2022.07.009


Rodrigo Arias-Cartin, Alexandre Uzel, Farida Seduk, Guillaume Gerbaud, Fabien Pierrel, Marianne Broc, Régine Lebrun, Bruno Guigliarelli, Axel Magalon, Stéphane Grimaldi, Anne Walburger.
Identification and characterization of a non-canonical menaquinone-linked formate dehydrogenase.
Journal of Biological Chemistry, 2021, 101384. DOI: 10.1016/j.jbc.2021.101384 HAL: hal-03431446v1


Ahmed Djeghader, Mélanie Rossotti, Saleh Abdulkarim, Frédéric Biaso, Guillaume Gerbaud, Wolfgang Nitschke, Barbara Schoepp-Cothenet, Tewfik Soulimane, Stephane Grimaldi.
Structural evidence for a reaction intermediate mimic in the active site of a sulfite dehydrogenase.
Chem. Commun., 2020, 56 (68), 9850 - 9853. DOI: 10.1039/D0CC03634J HAL: hal-02930401

Annalisa Pierro, Emilien Etienne, Guillaume Gerbaud, Bruno Guigliarelli, Stefano Ciurli, Valérie Belle, Barbara Zambelli, Elisabetta Mileo.
Nickel and GTP Modulate Helicobacter pylori UreG Structural Flexibility.
Biomolecules, 2020, 10 (7), 1062. DOI: 10.3390/biom10071062 HAL: hal-02902916v1


Eugénie Fournier, Sybille Tachon, Nicholas J. Fowler, Guillaume Gerbaud, Pascal Mansuelle, Pierre Dorlet, Sam P. De Visser, Valérie Belle, A. Jalila Simaan, Marlène Martinho.
The Hunt for the Closed Conformation of the Fruit‐Ripening Enzyme 1‐Aminocyclopropane‐1‐carboxylic Oxidase: A Combined Electron Paramagnetic Resonance and Molecular Dynamics Study.
Chem. Eur. J., 2019, 25 (60), 13766-13776. DOI: 10.1002/chem.201903003 HAL: hal-02303326v1

Kamal Zeamari, Guillaume Gerbaud, Sandrine Grosse, Vincent Fourmond, Florence Chaspoul, Frédéric Biaso, Pascal Arnoux, Monique Sabaty, David Pignol, Bruno Guigliarelli, Bénédicte Burlat.
Tuning the redox properties of a [4Fe-4S] center to modulate the activity of Mo-bisPGD periplasmic nitrate reductase.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2019, 1860 (5), 402 - 413. DOI: 10.1016/j.bbabio.2019.01.003 HAL: hal-02106668v1

Cyrielle Dol, Guillaume Gerbaud, Bruno Guigliarelli, Emily Bloch, Stéphane Gastaldi, Eric Besson.
Modulating lifetimes and relaxation times of phenoxyl radicals through their incorporation into different hybrid nanostructures.
Phys. Chem. Chem. Phys., 2019, 172 (29), 573 - 16344. DOI: 10.1039/C9CP03052B HAL: hal-02177931v1

Eugénie Fournier, Elisabetta Mileo, Emilien Etienne, Guillaume Gerbaud, Valérie Belle, Marlène Martinho.
Spin labels: spies in the heart of proteins.
Actualité Chimique, 2019, 443. (voir / see)


Ganesan Karthikeyan, Alessio Bonucci, Gilles Casano, Guillaume Gerbaud, Sébastien Abel, Virginie Thomé, Laurent Kodjabachian, Axel Magalon, Bruno Guigliarelli, Valérie Belle, Olivier Ouari, Elisabetta Mileo.
A Bioresistant Nitroxide Spin Label for In-Cell EPR Spectroscopy: In Vitro and In Oocytes Protein Structural Dynamics Studies.
Angew. Chem. Int. Ed., 2018, 57, 1366 - 1370. DOI: 10.1002/anie.201710184 HAL: hal-02000559v1


Nolwenn Le Breton, Tiona Adrianaivomananjaona, Guillaume Gerbaud, Emilien Etienne, Elena Bisetto, Alain Dautant, Bruno Guigliarelli, Francis Haraux, Marlène Martinho, Valérie Belle.
Dimerization interface and dynamic properties of yeast IF1 revealed by Site-Directed Spin Labeling EPR spectroscopy.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2016, 1857 (1), 89 - 97. DOI: 10.1016/j.bbabio.2015.10.010 HAL: hal-01413333v1

Eric Besson, Fabio Ziarelli, Emily Bloch, Guillaume Gerbaud, Séverine Queyroy, Stéphane Viel, Stéphane Gastaldi.
Silica materials with wall-embedded nitroxides provide efficient polarization matrices for dynamic nuclear polarization NMR.
Chem. Commun., 2016, 52 (32), 5531 - 5533. DOI: 10.1039/c6cc01809b HAL: hal-01415149v1


Nolwenn Le Breton, Marlène Martinho, Elisabetta Mileo, Emilien Etienne, Guillaume Gerbaud, Bruno Guigliarelli, Valérie Belle.
Exploring intrinsically disordered proteins using site-directed spin labeling electron paramagnetic resonance spectroscopy.
Front. Mol. Biosci., 2015, 2:21, 1 - 7. DOI: 10.3389/fmolb.2015.00021 HAL: hal-01429982v1