member photo

Directeur de Recherche, CNRS

+33 4 91 16 44 35

Equipe / Group: BIP 09

Nothing in the emergence and subsequent evolution of life makes sense except in the light of Bioenergetics (freely riffing on Dobzhansky’s catchphrase)
The extraordinary generation of order characterising living cells is driven by electrochemical disequilibria (i.e. tensions between reducing and oxidising redox compounds provided by the environment or internally induced by absoption of photons). At BIP09 we pursue a comparative study of diverse prokaryotic bioenergetic systems (both entire bioenergetic chains and individual enzymes) to infer the minimal common core of biological energy conversion. This common core potentially provides leads towards the type of free energy conversion which had driven life into existence in the first place. We furthermore use this information to investigate possible mineral precursors to life’s earliest bioenergetic systems.
For more detailed info, please visit our dedicated webpages

ORCID id: 0000-0003-2084-3032


Simon Duval, Kilian Zuchan, Frauke Baymann, Barbara Schoepp-Cothenet, Elbert Branscomb, Michael J. Russell, Wolfgang Nitschke.
Minerals and the emergence of life.
MILS, Metals, Microbes, and Minerals - The Biogeochemical Side of Life, 2021, 21, 135-157. DOI: 10.1515/9783110589771-011 HAL: hal-03163239v1

Robert van Lis, Yohann Couté, Sabine Brugière, Nicolas J. Tourasse, Benoist Laurent, Wolfgang Nitschke, Olivier Vallon, Ariane Atteia.
Phylogenetic and functional diversity of aldehyde-alcohol dehydrogenases in microalgae.
Plant Mol Biol, 2021. DOI: 10.1007/s11103-020-01105-9

Kilian Zuchan, Frauke Baymann, Carole Baffert, Myriam Brugna, Wolfgang Nitschke.
The dyad of the Y-junction- and a flavin module unites diverse redox enzymes.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2021, 1862 (6), 148401 -. DOI: 10.1016/j.bbabio.2021.148401


Simon Duval, Elbert Branscomb, Fabienne Trolard, Guilhem Bourrié, Olivier Grauby, Vasile Heresanu, Barbara Schoepp-Cothenet, Kilian Zuchan, Michael J. Russell, Wolfgang Nitschke.
On the why's and how's of clay minerals' importance in life's emergence.
Applied Clay Science, 2020, 195, 105737 -. DOI: 10.1016/j.clay.2020.105737 HAL: hal-02936347v1

Ahmed Djeghader, Mélanie Rossotti, Saleh Abdulkarim, Frédéric Biaso, Guillaume Gerbaud, Wolfgang Nitschke, Barbara Schoepp-Cothenet, Tewfik Soulimane, Stephane Grimaldi.
Structural evidence for a reaction intermediate mimic in the active site of a sulfite dehydrogenase.
Chem. Commun., 2020, 56 (68), 9850 - 9853. DOI: 10.1039/D0CC03634J HAL: hal-02930401

Julie Szyttenholm, Florence Chaspoul, Marielle Bauzan, Anne-Lise Ducluzeau, Mahmoud Hajj Chehade, Fabien Pierrel, Yann Denis, Wolfgang Nitschke, Barbara Schoepp-Cothenet.
The controversy on the ancestral arsenite oxidizing enzyme; deducing evolutionary histories with phylogeny and thermodynamics.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2020, 1861 (10), 148252 -. DOI: 10.1016/j.bbabio.2020.148252 HAL: hal-02896357v1


Sven De Causmaecker, Jeffrey S. Douglass, Andrea Fantuzzi, Wolfgang Nitschke, A. William Rutherford.
Energetics of the exchangeable quinone, QB, in Photosystem II.
Proc Natl Acad Sci USA, 2019, 1184 (39), 85 - 19463. DOI: 10.1073/pnas.1910675116 HAL: hal-02407784v1

Simon Duval, Frauke Baymann, Barbara Schoepp-Cothenet, Fabienne Trolard, Guilhem Bourrié, Olivier Grauby, Elbert Branscomb, Michael J. Russell, Wolfgang Nitschke.
Fougerite: the not so simple progenitor of the first cells.
Interface Focus, 2019, 323 (6), 93 -. DOI: 10.1098/rsfs.2019.0063 HAL: hal-02359667v1

Robert Van Lis, Sabine Brugière, Carole Baffert, Yohann Couté, Wolfgang Nitschke, Ariane Atteia.
Hybrid cluster proteins in a photosynthetic microalga.
FEBS J, 2019, 33 (1), 1870 -. DOI: 10.1111/febs.15025 HAL: hal-02284985v1


Wolfgang Nitschke.
Carbon Fixation: “Let Things Flow Naturally Forward in Whatever Way They Like”.
Current Biology, 2018, 28 (3), R110 - R112. DOI: 10.1016/j.cub.2017.12.039 HAL: hal-01709233v1

Frauke Baymann, Barbara Schoepp-Cothenet, Simon Duval, Marianne Guiral, Myriam Brugna, Carole Baffert, Michael J. Russell, Wolfgang Nitschke.
On the Natural History of Flavin-Based Electron Bifurcation.
Front. Microbiol., 2018, 8, 357 -. DOI: 10.3389/fmicb.2018.01357 HAL: hal-01828959v1


Taiki Motomura, Michihiro Suga, Rainer Hienerwadel, Akiko Nakagawa, Thanh-Lan Lai, Wolfgang Nitschke, Takahiro Kuma, Miwa Sugiura, Alain Boussac, Jian-Ren Shen.
Crystal structure and redox properties of a novel cyanobacterial heme protein with a His/Cys heme axial ligation and a Per-Arnt-Sim (PAS)-like domain.
J. Biol. Chem., 2017, 85 (23), 2891 - 9612. DOI: 10.1074/jbc.M116.746263 HAL: hal-01514729v1

Michael J. Russell, Wolfgang Nitschke.
Methane: Fuel or Exhaust at the Emergence of Life?.
Astrobiology, 2017, 17 (10), 1053 - 1066. DOI: 10.1089/ast.2016.1599 HAL: hal-01696601v1


Robert van Lis, Marion Popek, Yohann Couté, Artemis Kosta, Dominique Drapier, Wolfgang Nitschke, Ariane Atteia.
Concerted Up-regulation of Aldehyde/Alcohol Dehydrogenase (ADHE) and Starch in Chlamydomonas reinhardtii Increases Survival under Dark Anoxia.
J. Biol. Chem., 2016, 96 (6), 71 - 2410. DOI: 10.1074/jbc.M116.766048 HAL: hal-01430308v1

Lucie Bergdoll, Felix ten Brink, Wolfgang Nitschke, Daniel Picot, Frauke Baymann.
From low- to high-potential bioenergetic chains: Thermodynamic constraints of Q-cycle function.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2016, 1857 (9), 1569 - 1579. DOI: 10.1016/j.bbabio.2016.06.006 HAL: hal-01413250v1

Simon Duval, Joanne M. Santini, David Lemaire, Florence Chaspoul, Michael J. Russell, Stephane Grimaldi, Wolfgang Nitschke, Barbara Schoepp-Cothenet.
The H-bond network surrounding the pyranopterins modulates redox cooperativity in the molybdenum- bis PGD cofactor in arsenite oxidase.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2016, 1857 (9), 1353 - 1362. DOI: 10.1016/j.bbabio.2016.05.003 HAL: hal-01413292v1

Wei-Chun Kao, Thomas Kleinschroth, Wolfgang Nitschke, Frauke Baymann, Yashvin Neehaul, Petra Hellwig, Sebastian Richers, Janet Vonck, Michael Bott, Carola Hunte.
The obligate respiratory supercomplex from Actinobacteria.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2016, 1857 (10), 1705 - 1714. DOI: 10.1016/j.bbabio.2016.07.009 HAL: hal-01415865v1


Marie Catherine Sforna, Pascal Philippot, Andrea Somogyi, Mark A. van Zuilen, Kadda Medjoubi, Barbara Schoepp-Cothenet, Wolfgang Nitschke, Pieter T. Visscher.
Evidence for arsenic metabolism and cycling by microorganisms 2.7 billion years ago.
Nature Geosci, 2014, 16 (11), 523 - 815. DOI: 10.1038/ngeo2276 HAL: hal-01494482v1

Anne-Lise Ducluzeau, Barbara Schoepp-Cothenet, Frauke Baymann, Michael J. Russell, Wolfgang Nitschke.
Free energy conversion in the LUCA: Quo vadis?.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2014, 1837 (7), 982 - 988. DOI: 10.1016/j.bbabio.2013.12.005 HAL: hal-01493447v1

L. J. Bird, I. H. Saraiva, S. Park, E. O. Calcada, C. A. Salgueiro, W. Nitschke, R. O. Louro, D. K. Newman.
Nonredundant Roles for Cytochrome c2 and Two High-Potential Iron-Sulfur Proteins in the Photoferrotroph Rhodopseudomonas palustris TIE-1.
Journal of Bacteriology, 2014, 3 (Pt 5), 152 - 858. DOI: 10.1128/JB.00843-13

Michael J. Russell, Laura M. Barge, Rohit Bhartia, Dylan Bocanegra, Paul J. Bracher, Elbert Branscomb, Richard Kidd, Shawn McGlynn, David H. Meier, Wolfgang Nitschke, Takazo Shibuya, Steve Vance, Lauren White, Isik Kanik.
The Drive to Life on Wet and Icy Worlds.
Astrobiology, 2014, 14 (4), 308 - 343. DOI: 10.1089/ast.2013.1110 HAL: hal-01493520v1

Anne-Lise Ducluzeau, Barbara Schoepp-Cothenet, Robert van Lis, Frauke Baymann, Michael J. Russell, Wolfgang Nitschke.
The evolution of respiratory O 2 /NO reductases: an out-of-the-phylogenetic-box perspective.
J. R. Soc. Interface, 2014, 265 (98), 11 535 -. DOI: 10.1098/rsif.2014.0196 HAL: hal-01494539v1


Robert van Lis, Wolfgang Nitschke, Simon Duval, Barbara Schoepp-Cothenet.
Arsenics as bioenergetic substrates.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2013, 1827 (2), 176 - 188. DOI: 10.1016/j.bbabio.2012.08.007 HAL: hal-01601687v1

Wolfgang Nitschke, Michael J. Russell.
Beating the acetyl coenzyme A-pathway to the origin of life.
Phil. Trans. R. Soc. B, 2013, 181 (1622), 5750 -. DOI: 10.1098/rstb.2012.0258

F. ten Brink, B. Schoepp-Cothenet, R. van Lis, W. Nitschke, F. Baymann.
Multiple Rieske/cytb complexes in a single organism.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2013, 1827 (11-12), 1392 - 1406. DOI: 10.1016/j.bbabio.2013.03.003 HAL: hal-01607947v1

Wolfgang Nitschke, Shawn E. McGlynn, E. James Milner-White, Michael J. Russell.
On the antiquity of metalloenzymes and their substrates in bioenergetics.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2013, 1827 (8-9), 871 - 881. DOI: 10.1016/j.bbabio.2013.02.008

Barbara Schoepp-Cothenet, Robert van Lis, Ariane Atteia, Frauke Baymann, Line Capowiez, Anne-Lise Ducluzeau, Simon Duval, Felix ten Brink, Michael J. Russell, Wolfgang Nitschke.
On the universal core of bioenergetics.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2013, 1827 (2), 79 - 93. DOI: 10.1016/j.bbabio.2012.09.005 HAL: hal-01606377v1

Wolfgang Nitschke.
The evolutionary aspects of bioenergetic systems.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2013, 1827 (2), 61 -. DOI: 10.1016/j.bbabio.2012.10.011 HAL: hal-01929330v1

Michael J. Russell, Wolfgang Nitschke, Elbert Branscomb.
The inevitable journey to being.
Phil. Trans. R. Soc. B, 2013, 19 (1622), 1517 -. DOI: 10.1098/rstb.2012.0254 HAL: hal-00675995v1


Robert van Lis, Carole Baffert, Yohann Couté, Wolfgang Nitschke, Ariane Atteia.
Chlamydomonas reinhardtii Chloroplasts Contain a Homodimeric Pyruvate:Ferredoxin Oxidoreductase That Functions with FDX1.
Plant Physiol., 2012, 161 (1), 57 - 71. DOI: 10.1104/pp.112.208181 HAL: hal-01601845v1

Maria-Eirini Pandelia, Wolfgang Lubitz, Wolfgang Nitschke.
Evolution and diversification of Group 1 [NiFe] hydrogenases. Is there a phylogenetic marker for O2-tolerance?.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2012, 1817 (9), 1565 - 1575. DOI: 10.1016/j.bbabio.2012.04.012

Maria-Eirini Pandelia, Wolfgang Lubitz, Wolfgang Nitschke.
Evolution and diversification of Group 1 [NiFe] hydrogenases. Is there a phylogenetic marker for O2-tolerance?.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2012, 1817 (9), 1565 - 1575. DOI: 10.1016/j.bbabio.2012.04.012

Robert van Lis, Wolfgang Nitschke, Thomas P. Warelow, Line Capowiez, Joanne M. Santini, Barbara Schoepp-Cothenet.
Heterologously expressed arsenite oxidase: A system to study biogenesis and structure/function relationships of the enzyme family.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2012, 1817 (9), 1701 - 1708. DOI: 10.1016/j.bbabio.2012.06.001 HAL: hal-01601795v1

Frauke Baymann, Barbara Schoepp-Cothenet, Evelyne Lebrun, Robert van Lis, Wolfgang Nitschke.
Phylogeny of Rieske/cytb Complexes with a Special Focus on the Haloarchaeal Enzymes.
2012, 392 (8), 677 - 841. DOI: 10.1093/gbe/evs056 HAL: hal-01607945v1

Barbara Schoepp-Cothenet, Robert van Lis, Pascal Philippot, Axel Magalon, Michael J. Russell, Wolfgang Nitschke.
The ineluctable requirement for the trans-iron elements molybdenum and/or tungsten in the origin of life.
Sci Rep, 2012, 18 (1), 2714 -. DOI: 10.1038/srep00263 HAL: hal-01608654v1

K. Kohzuma, C. Dal Bosco, A. Kanazawa, A. Dhingra, W. Nitschke, J. Meurer, D. M. Kramer.
Thioredoxin-insensitive plastid ATP synthase that performs moonlighting functions.
Proceedings of the National Academy of Sciences, 2012, 105 (48), 18818 - 3298. DOI: 10.1073/pnas.1115728109


Olga Kolaj-Robin, Sarah R. O'Kane, Wolfgang Nitschke, Christophe Léger, Frauke Baymann, Tewfik Soulimane.
Biochemical and biophysical characterization of succinate: Quinone reductase from Thermus thermophilus.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2011, 1807 (1), 68 - 79. DOI: 10.1016/j.bbabio.2010.10.009 HAL: hal-00999887v1

M.-E. Pandelia, W. Nitschke, P. Infossi, M.-T. Giudici-Orticoni, E. Bill, W. Lubitz.
Characterization of a unique [FeS] cluster in the electron transfer chain of the oxygen tolerant [NiFe] hydrogenase from Aquifex aeolicus.
Proceedings of the National Academy of Sciences, 2011, 106 (49), 20681 - 6102. DOI: 10.1073/pnas.1100610108

B. Schoepp-Cothenet, W. Nitschke, L. M. Barge, A. Ponce, M. J. Russell, A. I. Tsapin.
Comment on "A Bacterium That Can Grow by Using Arsenic Instead of Phosphorus".
Science, 2011, 323 (5914), 583c - 1149. DOI: 10.1126/science.1201438

Wolfgang Nitschke, Michael J. Russell.
Redox bifurcations: Mechanisms and importance to life now, and at its origin.
Bioessays, 2011, 34 (2), 9 - 109. DOI: 10.1002/bies.201100134


Aurélie Lieutaud, Robert van Lis, Simon Duval, Line Capowiez, Daniel Muller, Régine Lebrun, Sabrina Lignon, Marie-Laure Fardeau, Marie-Claire Lett, Wolfgang Nitschke, Barbara Schoepp-Cothenet.
Arsenite Oxidase from Ralstonia sp. 22.
J. Biol. Chem., 2010, 35 (27), 3302 - 20441. DOI: 10.1074/jbc.M110.113761 HAL: hal-01602032v1

Bahia Khalfaoui Hassani, Chantal Astier, Wolfgang Nitschke, Soufian Ouchane.
CtpA, a Copper-translocating P-type ATPase Involved in the Biogenesis of Multiple Copper-requiring Enzymes.
J. Biol. Chem., 2010, 64 (25), 2710 - 19337. DOI: 10.1074/jbc.M110.116020

F. Baymann, W. Nitschke.
Heliobacterial Rieske/cytb complex.
Photosynth Res, 2010, 90 (2-3), 4145 - 187. DOI: 10.1007/s11120-009-9524-1

Simon Duval, Joanne M. Santini, Wolfgang Nitschke, Russ Hille, Barbara Schoepp-Cothenet.
The Small Subunit AroB of Arsenite Oxidase.
J. Biol. Chem., 2010, Vol. I (27), 945 - 20451. DOI: 10.1074/jbc.M110.113811

W. Nitschke, R. van Lis, B. Schoepp-Cothenet, F. Baymann.
The “green” phylogenetic clade of Rieske/cytb complexes.
Photosynth Res, 2010, 128 (2-3), 14246 - 355. DOI: 10.1007/s11120-010-9532-1 HAL: hal-01607249v1


B. Schoepp-Cothenet, S. Duval, J. M. Santini, W. Nitschke.
Comment on "Arsenic (III) Fuels Anoxygenic Photosynthesis in Hot Spring Biofilms from Mono Lake, California".
Science, 2009, 8 (5621), 206 - 583c. DOI: 10.1126/science.1164967

Wolfgang Nitschke, Michael J. Russell.
Hydrothermal Focusing of Chemical and Chemiosmotic Energy, Supported by Delivery of Catalytic Fe, Ni, Mo/W, Co, S and Se, Forced Life to Emerge.
J Mol Evol, 2009, 19 (5), 179 - 496. DOI: 10.1007/s00239-009-9289-3

B. Schoepp-Cothenet, C. Lieutaud, F. Baymann, A. Vermeglio, T. Friedrich, D. M. Kramer, W. Nitschke.
Menaquinone as pool quinone in a purple bacterium.
Proceedings of the National Academy of Sciences, 2009, 5 (3), 151 - 8554. DOI: 10.1073/pnas.0813173106

Anne-Lise Ducluzeau, Robert van Lis, Simon Duval, Barbara Schoepp-Cothenet, Michael J. Russell, Wolfgang Nitschke.
Was nitric oxide the first deep electron sink?.
Trends in Biochemical Sciences, 2009, 34 (1), 9 - 15. DOI: 10.1016/j.tibs.2008.10.005 HAL: hal-01607251v1


Simon Duval, Anne-Lise Ducluzeau, Wolfgang Nitschke, Barbara Schoepp-Cothenet.
Enzyme phylogenies as markers for the oxidation state of the environment: The case of respiratory arsenate reductase and related enzymes.
BMC Evolutionary Biology, 2008, 8 (1), 206 -. DOI: 10.1186/1471-2148-8-206

A.-L. Ducluzeau, S. Ouchane, W. Nitschke.
The cbb3 Oxidases Are an Ancient Innovation of the Domain Bacteria.
Molecular Biology and Evolution, 2008, 99 (1), 194 - 1166. DOI: 10.1093/molbev/msn062


Daniel Muller, Claudine Médigue, Sandrine Koechler, Valérie Barbe, Mohamed Barakat, Emmanuel Talla, Violaine Bonnefoy, Evelyne Krin, Florence Arsène-Ploetze, Christine Carapito, Michael Chandler, Benoît Cournoyer, Stéphane Cruveiller, Caroline Dossat, Sim.
A Tale of Two Oxidation States: Bacterial Colonization of Arsenic-Rich Environments.
PLoS Genet, 2007, 73 (4), 1917 -. DOI: 10.1371/journal.pgen.0030053 HAL: hal-00340034v1

Eric Pilet, Wolfgang Nitschke, Ursula Liebl, Marten H. Vos.
Accommodation of NO in the active site of mammalian and bacterial cytochrome c oxidase aa3.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2007, 1767 (5), 387 - 392. DOI: 10.1016/j.bbabio.2007.03.001 HAL: hal-00324353v1

F. Baymann, F. Giusti, D. Picot, W. Nitschke.
The ci/bH moiety in the b6f complex studied by EPR: A pair of strongly interacting hemes.
Proceedings of the National Academy of Sciences, 2007, 1100 (1), 128 - 524. DOI: 10.1073/pnas.0606369104 HAL: hal-02329862v1


Gérard Lipowski, Ursula Liebl, Bruno Guigliarelli, Wolfgang Nitschke, Barbara Schoepp-Cothenet.
Conformation of the c 552 : aa 3 electron transfer complex in Paracoccus denitrificans studied by EPR on oriented samples.
2006, 409 (25), 128 - 5992. DOI: 10.1016/j.febslet.2006.09.038 HAL: hal-00824462v1

Evelyne Lebrun, Joanne M. Santini, Myriam Brugna, Anne-Lise Ducluzeau, Soufian Ouchane, Barbara Schoepp-Cothenet, Frauke Baymann, Wolfgang Nitschke.
The Rieske Protein: A Case Study on the Pitfalls of Multiple Sequence Alignments and Phylogenetic Reconstruction.
2006, 23 (6), 1180 - 1191. DOI: 10.1093/molbev/msk010 HAL: hal-00132690v1


Marianne Guiral, Gisèle Leroy, Pierre Bianco, Philippe Gallice, Bruno Guigliarelli, Mireille Bruschi, Wolfgang Nitschke, Marie-Thérèse Giudici-Orticoni.
Interaction and electron transfer between the high molecular weight cytochrome and cytochrome c3 from Desulfovibrio vulgaris Hildenborough: Kinetic, microcalorimetric, EPR and electrochemical studies.
Biochimica et Biophysica Acta (BBA) - General Subjects, 2005, 1723 (1-3), 45 - 54. DOI: 10.1016/j.bbagen.2005.01.015

Soufian Ouchane, Wolfgang Nitschke, Pierre Bianco, André Vermeglio, Chantal Astier.
Multiple Rieske genes in prokaryotes: exchangeable Rieske subunits in the cytochrome bc1-complex of Rubrivivax gelatinosus.
2005, 392 (1), 677 - 275. DOI: 10.1111/j.1365-2958.2005.04685.x

C. Lieutaud, J. Alric, M. Bauzan, W. Nitschke, B. Schoepp-Cothenet.
Study of the high-potential iron sulfur protein in Halorhodospira halophila confirms that it is distinct from cytochrome c as electron carrier.
Proceedings of the National Academy of Sciences, 2005, 1229 (2), 81 - 3265. DOI: 10.1073/pnas.0407768102 HAL: hal-00339973v1


F. Baymann, E. Lebrun, W. Nitschke.
Mitochondrial cytochrome c1 is a collapsed di-heme cytochrome.
Proceedings of the National Academy of Sciences, 2004, 179 (5), 1734 - 17740. DOI: 10.1073/pnas.0407442101

Eric Pilet, Wolfgang Nitschke, Fabrice Rappaport, Tewfik Soulimane, Jean-Christophe Lambry, Ursula Liebl, Marten H. Vos.
NO Binding and Dynamics in Reduced Heme−Copper Oxidases aa 3 from Paracoccus denitrificans and ba 3 from Thermus thermophilus.
Biochemistry, 2004, 43 (44), 14118 - 14127. DOI: 10.1021/bi0488808 HAL: hal-00836426v1

Jean Alric, Yusuke Tsukatani, Makoto Yoshida, Katsumi Matsuura, Keizo Shimada, Rainer Hienerwadel, Barbara Schoepp-Cothenet, Wolfgang Nitschke, Kenji V. P. Nagashima, André Verméglio.
Structural and Functional Characterization of the Unusual Triheme Cytochrome Bound to the Reaction Center of Rhodovulum sulfidophilum.
J. Biol. Chem., 2004, 108 (25), 1163 - 26097. DOI: 10.1074/jbc.M400361200


E. Lebrun, M. Brugna, F. Baymann, D. Muller, D. Lievremont, M.-C. Lett, W. Nitschke.
Arsenite Oxidase, an Ancient Bioenergetic Enzyme.
2003, 20 (5), 686 - 693. DOI: 10.1093/molbev/msg071 HAL: hal-00113712v1

Clément Lieutaud, Wolfgang Nitschke, André Verméglio, Pierre Parot, Barbara Schoepp-Cothenet.
HiPIP in Rubrivivax gelatinosus is firmly associated to the membrane in a conformation efficient for electron transfer towards the photosynthetic reaction centre.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2003, 1557, 83 - 90. DOI: 10.1016/S0005-2728(02)00397-3

Frauke Baymann, Evelyne Lebrun, Myriam Brugna, Barbara Schoepp–Cothenet, Marie–Thérèse Giudici–Orticoni, Wolfgang Nitschke.
The redox protein construction kit: pre-last universal common ancestor evolution of energy-conserving enzymes.
Phil. Trans. R. Soc. Lond. B, 2003, 180 (1429), 1460 - 274. DOI: 10.1098/rstb.2002.1184 HAL: hal-00343715v1

Chantal Abergel, Wolfgang Nitschke, Guillaume Malarte, Mireille Bruschi, Jean-Michel Claverie, Marie-Thérèse Giudici-Orticoni.
The Structure of Acidithiobacillus ferrooxidans c4-Cytochrome.
Structure, 2003, 11 (5), 547 - 555. DOI: 10.1016/S0969-2126(03)00072-8

Marianne Brugna-Guiral, Pascale Tron, Wolfgang Nitschke, Karl-Otto Stetter, Benedicte Burlat, Bruno Guigliarelli, Mireille Bruschi, Marie Thérèse Giudici-Orticoni.
[NiFe] hydrogenases from the hyperthermophilic bacterium Aquifex aeolicus: properties, function, and phylogenetics.
Extremophiles, 2003, 139 (2), 139 - 157. DOI: 10.1007/s00792-002-0306-3


Frauke Baymann, Pascale Tron, Barbara Schoepp-Cothenet, Corinne Aubert, Pierre Bianco, Karl-Otto Stetter, Wolfgang Nitschke, Michael Schütz.
Cytochromes c 555 from the Hyperthermophilic Bacterium Aquifex aeolicus (VF5). 1. Characterization of Two Highly Homologous, Soluble and Membranous, Cytochromes.
Biochemistry, 2001, 40 (45), 13681 - 13689. DOI: 10.1021/bi011201y

Frauke Baymann, Myriam Brugna, Ulrich Mühlenhoff, Wolfgang Nitschke.
Daddy, where did (PS)I come from?.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2001, 1507 (1-3), 291 - 310. DOI: 10.1016/S0005-2728(01)00209-2

Guillermo Montoya, Kai te Kaat, Simon Rodgers, Wolfgang Nitschke, Irmgard Sinning.
The cytochrome bc1 complex from Rhodovulum sulfidophilum is a dimer with six quinones per monomer and an additional 6-kDa component.
European Journal of Biochemistry, 2001, 265 (3), 17005 - 718. DOI: 10.1046/j.1432-1327.1999.00094.x

Barbara Schoepp-Cothenet, Michael Schütz, Frauke Baymann, Myriam Brugna, Wolfgang Nitschke, Hannu Myllykallio, Christian Schmidt.
The membrane-extrinsic domain of cytochrome b 558/566 from the Archaeon Sulfolobus acidocaldarius performs pivoting movements with respect to the membrane surface.
2001, 16 (3), 544 - 376. DOI: 10.1016/S0014-5793(00)02357-7


M. Brugna, S. Rodgers, A. Schricker, G. Montoya, M. Kazmeier, W. Nitschke, I. Sinning.
A spectroscopic method for observing the domain movement of the Rieske iron-sulfur protein.
Proceedings of the National Academy of Sciences, 2000, 1275 (1-2), 54 - 2074. DOI: 10.1073/pnas.030539897

Marie-Thérèse Giudici-Orticoni, Gisèle Leroy, Wolfgang Nitschke, Mireille Bruschi.
Characterization of a New Dihemic c 4 -Type Cytochrome Isolated from Thiobacillus ferrooxidans.
Biochemistry, 2000, 39 (24), 7205 - 7211. DOI: 10.1021/bi992846p

Michael Schütz, Myriam Brugna, Evelyne Lebrun, Frauke Baymann, Robert Huber, Karl-Otto Stetter, Günter Hauska, René Toci, Danielle Lemesle-Meunier, Pascale Tron, Christian Schmidt, Wolfgang Nitschke.
Early Evolution of Cytochrome bc Complexes.
Journal of Molecular Biology, 2000, 300 (4), 663 - 675. DOI: 10.1006/jmbi.2000.3915


Franke Baymann, Francesca Zito, Richard Kuras, Limor Minai, Wolfgang Nitschke, Francis-André Wollman.
Functional Characterization of Chlamydomonas Mutants Defective in Cytochrome f Maturation.
J. Biol. Chem., 1999, 3 (33), 243 - 22967. DOI: 10.1074/jbc.274.33.22957

Marie-Thérèse Giudici-Orticoni, Françoise Guerlesquin, Mireille Bruschi, Wolfgang Nitschke.
Interaction-induced Redox Switch in the Electron Transfer Complex Rusticyanin-Cytochrome c 4.
J. Biol. Chem., 1999, 265 (43), 2768 - 30369. DOI: 10.1074/jbc.274.43.30365

Amina Elbehti, Wolfgang Nitschke, Pascale Tron, Caroline Michel, Danielle Lemesle-Meunier.
Redox Components of Cytochrome bc -type Enzymes in Acidophilic Prokaryotes.
J. Biol. Chem., 1999, 266 (24), 17838 - 16765. DOI: 10.1074/jbc.274.24.16760

Myriam Brugna, Wolfgang Nitschke, Marcel Asso, Bruno Guigliarelli, Danielle Lemesle-Meunier, Christian Schmidt.
Redox Components of Cytochrome bc -type Enzymes in Acidophilic Prokaryotes.
J. Biol. Chem., 1999, 261 (24), 2768 - 16772. DOI: 10.1074/jbc.274.24.16766

Barbara Schoepp, Myriam Brugna, Astrid Riedel, Wolfgang Nitschke, David M. Kramer.
The Q o -site inhibitor DBMIB favours the proximal position of the chloroplast Rieske protein and induces a p K -shift of the redox-linked proton.
1999, 112 (3), 535 - 250. DOI: 10.1016/S0014-5793(99)00511-6


Detlef Bentrop, Ivano Bertini, Claudio Luchinat, Wolfgang Nitschke, Ulrich Mühlenhoff.
Characterization of the Unbound 2[Fe 4 S 4 ]-Ferredoxin-Like Photosystem I Subunit PsaC from the Cyanobacterium Synechococcus elongatus †.
Biochemistry, 1997, 36 (44), 13629 - 13637. DOI: 10.1021/bi9714058

David M. Kramer, Barbara Schoepp, Ursula Liebl, Wolfgang Nitschke.
Cyclic Electron Transfer in Heliobacillus mobilis Involving a Menaquinol-Oxidizing Cytochrome bc Complex and an RCI-Type Reaction Center †.
Biochemistry, 1997, 36 (14), 4203 - 4211. DOI: 10.1021/bi962241i

Delphine Albouy, James N. Sturgis, Ute Feiler, Wolfgang Nitschke, Bruno Robert.
Membrane-Associated c -type Cytochromes from the Green Sulfur Bacterium Chlorobium limicola forma thiosulfatophilum :  Purification and Characterization of Cytochrome.
Biochemistry, 1997, 36 (7), 1927 - 1932. DOI: 10.1021/bi962624g